489-59-8

489-59-8 structure

Name: isocytidine
Chemical Name: 2-Amino-1-(β-D-ribofuranosyl)-4(1H)-pyrimidinone
CAS Number: 489-59-8
Molecular Formula: C₉H₁₃N₃O₅
Molecular Weight: 243.22
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2016-08-01 04:27:16
Modify Date: 2023-01-15 11:58:39
2-Amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

Name	2-Amino-1-(β-D-ribofuranosyl)-4(1H)-pyrimidinone
Synonyms	Isocytidine

Description	2-Amino-1-β-D-ribofuranosyl-4(1H)-pyrimidinone is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Others
References	[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.