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820959-17-9

820959-17-9 structure
820959-17-9 structure
  • Name: Acetyl tetrapeptide-5
  • Chemical Name: (2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
  • CAS Number: 820959-17-9
  • Molecular Formula: C20H28N8O7
  • Molecular Weight: 492.486
  • Catalog: Biochemical Amino acids and their derivatives Histidine derivative
  • Create Date: 2018-02-16 08:00:00
  • Modify Date: 2024-01-07 11:47:30
  • Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care[1][2][3].

Name (2S)-2-[[(2S)-2-[[(2S)-2-(3-acetamidopropanoylamino)-3-(1H-imidazol-5-yl)propanoyl]amino]-3-hydroxypropanoyl]amino]-3-(1H-imidazol-5-yl)propanoic acid
Synonyms N-Acetyl-β-alanyl-L-histidyl-L-seryl-l-histidin
UNII-Y1DFQ308G8
Eyeseryl
L-Histidine, N-acetyl-β-alanyl-L-histidyl-L-seryl-
N-Acetyl-β-alanyl-L-histidyl-L-seryl-L-histidine
Acetyl tetrapeptide-5
Description Acetyl tetrapeptide-5 inhibits glycosylation and ACE-1 activity. Acetyl tetrapeptide-5 reduces edema and relieves vascular pressure by improving the vascular system and strengthening the skin under the eyes. Acetyl tetrapeptide-5 can be used in the research of Antioxidant, anti-aging skin care[1][2][3].
Related Catalog
Target

ACE-1[1]

In Vitro Acetyl tetrapeptide-5 (100 μg/mL) inhibits angiotensin-converting enzyme 1 (ACE-1) activity[1].
References

[1]. Yun Wu, et al. Protective and Anti-Aging Effects of 5 Cosmeceutical Peptide Mixtures on Hydrogen Peroxide-Induced Premature Senescence in Human Skin Fibroblasts. Skin Pharmacol Physiol. 2021;34(4):194-202.

[2]. Lijuan Zhang, et al. Cosmeceuticals and peptides. Clin Dermatol. 2009 Sep-Oct;27(5):485-94.

[3]. Puig A , et al. "Eyeseryl® and Leuphasyl®: synthetic peptides as advanced cosmetic actives. Cosmet Sci Technol (2006): 164-75.

Density 1.4±0.1 g/cm3
Boiling Point 1237.3±65.0 °C at 760 mmHg
Molecular Formula C20H28N8O7
Molecular Weight 492.486
Flash Point 702.1±34.3 °C
Exact Mass 492.208099
PSA 245.25000
LogP -3.79
Vapour Pressure 0.0±0.3 mmHg at 25°C
Index of Refraction 1.611
Storage condition 2-8℃