7803-88-5

7803-88-5 structure

Name: 6-O-Methyl Guanosine
Chemical Name: (2R,3S,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
CAS Number: 7803-88-5
Molecular Formula: C₁₁H₁₅N₅O₅
Molecular Weight: 297.267
Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
Create Date: 2017-10-22 09:51:32
Modify Date: 2024-01-06 10:22:18
6-O-Methyl Guanosine is a modified nucleoside[1]. 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line[2].

Name	(2R,3S,4R,5R)-2-(2-amino-6-methoxypurin-9-yl)-5-(hydroxymethyl)oxolane-3,4-diol
Synonyms	9H-Purin-2-amine, 6-methoxy-9-β-D-ribofuranosyl- 6-O-METHYLGUANOSINE Guanosine,o-methyl 2-amino-6-methoxypurine riboside 6-Methoxy-6-deoxoguanosine o-methoxydeoxyguanosine O-Methylguanosine 6-Methoxy-9-(β-D-ribofuranosyl)-9H-purin-2-amine O6-METHYLGUANOSINE o-methyl-guanosin 2-Amino-6-methoxypurine Ribonucleoside

Description	6-O-Methyl Guanosine is a modified nucleoside[1]. 6-O-Methyl Guanosine (6-methylguanosine) inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line[2].
Related Catalog	Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog Research Areas >> Inflammation/Immunology
References	[1]. Grasby JA, et al. The synthesis of oligoribonucleotides containing O6-methylguanosine: the role of conserved guanosine residues in hammerhead ribozyme cleavage. Nucleic Acids Res. 1993 Sep 25;21(19):4444-50. [2]. Thielmann HW, et al. 6-Methylguanine and 6-methylguanosine inhibit colony-forming ability in a malignant xeroderma pigmentosum cell line but not in other xeroderma pigmentosum and normal human fibroblast strains after treatment with 1-(2-chloroethyl)-1-nitroso-3-(2-hydroxyethyl)-urea. J Cancer Res Clin Oncol. 1987;113(1):67-72.

REFERENCE :: ENMUDM Environmental Mutagenesis. (New York, NY) V.1-9, 1979-87. For publisher information, see EMMUEG. Volume(issue)/page/year: 4,321,1982