33421-40-8

33421-40-8 structure

Name: 2-Amino-5-phenylpyridine
Chemical Name: 5-phenylpyridin-2-amine
CAS Number: 33421-40-8
Molecular Formula: C₁₁H₁₀N₂
Molecular Weight: 170.21000
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Pyridine derivative
Create Date: 2018-04-25 08:00:00
Modify Date: 2025-08-25 08:18:49
2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic[1][2].

Name	5-phenylpyridin-2-amine
Synonyms	5-phenyl-2-aminopyridine 5-phenyl-pyridin-2-ylamine 5-phenyl-2-pyridinamine 2-Amino-5-phenylpyridine 2-Pyridinamine,5-phenyl 5-Phenylpyridin-2-amine MFCD01692452 Pyridine,2-amino-5-phenyl Phe-P-1

Description	2-Amino-5-phenylpyridine is a mutagenic heterocyclic aromatic amine that is formed by pyrolysis of phenylalanine in proteins. 2-Amino-5-phenylpyridine is in broiled sardines and is considered as potentially carcinogenic[1][2].
Related Catalog	Research Areas >> Cancer
In Vitro	On the other hand, the chemical structure of 5-phenyl-2-pyridinamine (PPA) shows a great resemblance to the aminobiphenyls, another well known class of carcinogenic aromatic amines[2].
References	[1]. Dooley KL, et al. Comparative carcinogenicity of the food pyrolysis product, 2-amino-5-phenylpyridine, and the known human carcinogen, 4-aminobiphenyl, in the neonatal B6C3F1 mouse. Cancer Lett. 1988 Jul;41(1):99-103. [2]. Stavenuiter JF, et al. Syntheses of 5-phenyl-2-pyridinamine, a possibly carcinogenic pyrolysis product of phenylalanine, and some of its putative metabolites. Carcinogenesis. 1985 Jan;6(1):13-9.

REFERENCE :: CPBTAL Chemical and Pharmaceutical Bulletin. (Japan Pub. Trading Co., USA, 1255 Howard St., San Francisco, CA 94103) V.6- 1958- Volume(issue)/page/year: 26,611,1978