528851-31-2

528851-31-2 structure

Name: desethylene ciprofloxacin, hydrochloride
Chemical Name: 7-(2-aminoethylamino)-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid,hydrochloride
CAS Number: 528851-31-2
Molecular Formula: C₁₅H₁₇ClFN₃O₃
Molecular Weight: 341.77
Catalog: analytical chemistry Standard Pharmacopoeia Standards and Magazine Standards
Create Date: 2016-11-29 06:39:28
Modify Date: 2025-08-23 10:19:00
Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity[1].

Name	7-(2-aminoethylamino)-1-cyclopropyl-6-fluoro-4-oxoquinoline-3-carboxylic acid,hydrochloride
Synonyms	Enrofloxacin Imp. G (EP),HCl Desethylene Ciprofloxacin,Hydrochloride 7-[(2-amino-ethyl)amino]-1-cyclopropyl-1,4-dihydro-6-fluoro-4-oxo-quinoline-3-carboxylic acid hydrochloride BAY-r 3964,M1-Ciprofloxacin,7-[(2-Aminoethyl)amino]-1-cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-3-quinolinecarboxylic Acid

Description	Desethylene Ciprofloxacin hydrochloride is a major metabolite of Ciprofloxacin (HY-B0356). Ciprofloxacin is an orally active topoisomerase IV inhibitor. Desethylene Ciprofloxacin hydrochloride has antibacterial activity[1].
Related Catalog	Research Areas >> Infection Signaling Pathways >> Anti-infection >> Bacterial
References	[1]. Šíma M, et al. Factors Affecting the Metabolic Conversion of Ciprofloxacin and Exposure to Its Main Active Metabolites in Critically Ill Patients: Population Pharmacokinetic Analysis of Desethylene Ciprofloxacin. Pharmaceutics. 2022 Aug 4;14(8):1627.

Melting Point	>240ºC dec.
Molecular Formula	C₁₅H₁₇ClFN₃O₃
Molecular Weight	341.77
Exact Mass	341.09400
PSA	97.35000
LogP	3.11960
Storage condition	-20°C Freezer, Under Inert Atmosphere

86393-33-1

107-15-3

528851-30-1

528851-31-2

Literature: WO2004/101590 A1, ; Page 32-33 ;

Precursor 2
86393-33-1 107-15-3
DownStream 0