547-65-9

547-65-9 structure

Name: Tulipalin A
Chemical Name: α-methylene γ-butyrolactone
CAS Number: 547-65-9
Molecular Formula: C₅H₆O₂
Molecular Weight: 98.100
Catalog: Chemical reagent Organic reagent Ester Lactone compound
Create Date: 2018-10-01 13:33:15
Modify Date: 2024-01-02 19:14:54
Tulipalin A (α-Methylene butyrolactone) is a toxic glycoside isolated from the tulip bulbs. Tulipalin A is a causative allergen that induces Allergic contact dermatitides[1]. Tulipalin A (α-Methylene butyrolactone) at low dose affects the functionality of immune cells, such as Jurkat T cells[2].

Name	α-methylene γ-butyrolactone
Synonyms	3-Methylenedihydrofuran-2(3H)-one 2(3H)-Furanone, dihydro-3-methylene- 3-methylideneoxolan-2-one MFCD00005407 EINECS 208-931-6 alpha-methylene gamma-butyrolactone 2-Methylenebutyrolactone 3-Methylenedihydro-2(3H)-furanone α-Methylene-γ-butyrolactone

Description	Tulipalin A (α-Methylene butyrolactone) is a toxic glycoside isolated from the tulip bulbs. Tulipalin A is a causative allergen that induces Allergic contact dermatitides[1]. Tulipalin A (α-Methylene butyrolactone) at low dose affects the functionality of immune cells, such as Jurkat T cells[2].
References	[1]. Zwicker P, et al.A proteomic approach for the identification of immunotoxic properties of Tulipalin A.Proteomics. 2016 Dec;16(23):2997-3008. [2]. McCluskey J, et al. Tulipalin A induced phytotoxicity.Int J Crit Illn Inj Sci. 2014 Apr;4(2):181-3.

Symbol	GHS02, GHS07
Signal Word	Warning
Hazard Statements	H226-H317-H412
Precautionary Statements	P210-P280-P370 + P378
Personal Protective Equipment	Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
Hazard Codes	Xn
Risk Phrases	R42/43:May cause sensitization by inhalation and skin contact .
Safety Phrases	S23-S36/37
RIDADR	1993
WGK Germany	3
Packaging Group	III
Hazard Class	3.2
HS Code	2932209090