Tulipalin A structure
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Common Name | Tulipalin A | ||
|---|---|---|---|---|
| CAS Number | 547-65-9 | Molecular Weight | 98.100 | |
| Density | 1.1±0.1 g/cm3 | Boiling Point | 204.4±0.0 °C at 760 mmHg | |
| Molecular Formula | C5H6O2 | Melting Point | N/A | |
| MSDS | Chinese USA | Flash Point | 37.2±0.0 °C | |
| Symbol |
GHS02, GHS07 |
Signal Word | Warning | |
Use of Tulipalin ATulipalin A (α-Methylene butyrolactone) is a toxic glycoside isolated from the tulip bulbs. Tulipalin A is a causative allergen that induces Allergic contact dermatitides[1]. Tulipalin A (α-Methylene butyrolactone) at low dose affects the functionality of immune cells, such as Jurkat T cells[2]. |
| Name | α-methylene γ-butyrolactone |
|---|---|
| Synonym | More Synonyms |
| Description | Tulipalin A (α-Methylene butyrolactone) is a toxic glycoside isolated from the tulip bulbs. Tulipalin A is a causative allergen that induces Allergic contact dermatitides[1]. Tulipalin A (α-Methylene butyrolactone) at low dose affects the functionality of immune cells, such as Jurkat T cells[2]. |
|---|---|
| References |
[2]. McCluskey J, et al. Tulipalin A induced phytotoxicity.Int J Crit Illn Inj Sci. 2014 Apr;4(2):181-3. |
| Density | 1.1±0.1 g/cm3 |
|---|---|
| Boiling Point | 204.4±0.0 °C at 760 mmHg |
| Molecular Formula | C5H6O2 |
| Molecular Weight | 98.100 |
| Flash Point | 37.2±0.0 °C |
| Exact Mass | 98.036781 |
| PSA | 26.30000 |
| LogP | -0.06 |
| Vapour Pressure | 0.3±0.4 mmHg at 25°C |
| Index of Refraction | 1.452 |
| Storage condition | 2-8°C |
| Symbol |
GHS02, GHS07 |
|---|---|
| Signal Word | Warning |
| Hazard Statements | H226-H317-H412 |
| Precautionary Statements | P210-P280-P370 + P378 |
| Personal Protective Equipment | Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter |
| Hazard Codes | Xn |
| Risk Phrases | R42/43:May cause sensitization by inhalation and skin contact . |
| Safety Phrases | S23-S36/37 |
| RIDADR | 1993 |
| WGK Germany | 3 |
| Packaging Group | III |
| Hazard Class | 3.2 |
| HS Code | 2932209090 |
| Precursor 10 | |
|---|---|
| DownStream 9 | |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |
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Design and synthesis of spiro derivatives of parthenin as novel anti-cancer agents.
Eur. J. Med. Chem. 46 , 3210-7, (2011) Several novel spiro derivatives of parthenin (1) have been synthesized by the dipolar cycloaddition using various dipoles viz; benzonitrile oxides, nitrones and azides with exocyclic double bond of C ... |
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Construction of spiro-fused 2-oxindole/α-methylene- γ-butyrolactone systems with extremely high enantioselectivity via indium-catalyzed amide allylation of N-methyl isatin.
Org. Lett. 15(24) , 6182-5, (2013) A remarkably effective method allowing an extremely high enantioselective synthesis of the spiro-fused 2-oxindole/α-methylene-γ-butyrolactones is described. The key strategy lies in the use of indium-... |
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Highly stereoselective synthesis of (Z)- and (E)-chloro-substituted-α-methylene-γ-butyrolactone by possibly controlling cis- and trans-chloropalladation.
Mol. Divers. 17(1) , 1-7, (2013) A palladium-catalyzed selective synthesis of cis- or trans-chloro-substituted-α-methylene-γ-butyrolactones from single substrate (propiolic acid) has been realized by controlling cis- or trans-chlorop... |
| 3-Methylenedihydrofuran-2(3H)-one |
| 2(3H)-Furanone, dihydro-3-methylene- |
| 3-methylideneoxolan-2-one |
| MFCD00005407 |
| EINECS 208-931-6 |
| alpha-methylene gamma-butyrolactone |
| 2-Methylenebutyrolactone |
| 3-Methylenedihydro-2(3H)-furanone |
| α-Methylene-γ-butyrolactone |