524-81-2
524-81-2 structure
- Name: Mebhydrolin
- Chemical Name: 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole
- CAS Number: 524-81-2
- Molecular Formula: C19H20N2
- Molecular Weight: 276.37600
- Catalog: Signaling Pathways GPCR/G Protein Histamine Receptor
- Create Date: 2018-05-23 08:00:00
- Modify Date: 2025-08-25 20:20:46
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Mebhydrolin is a specific histamine H1 receptor antagonist.
| Name | 5-benzyl-2-methyl-3,4-dihydro-1H-pyrido[4,3-b]indole |
|---|---|
| Synonyms |
Mebhydrolin
5-Benzyl-2,3,4,5-tetrahydro-2-methyl-1H-pyrido[4,3-b]indol Mebhydrolinum [INN-Latin] Mebhydroline 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indole 5-Benzyl-2-methyl-2,3,4,5-tetrahydro-1H-pyrido[4,3-b]indol 9-benzyl-3-methyl-1,2,3,4-tetrahydro-3-carboline 3-methyl-9-benzyl-1,2,3,4-tetrahydrocarboline Mebhydroline [INN-French] Mebhidrolina [INN-Spanish] EINECS 208-364-4 |
| Description | Mebhydrolin is a specific histamine H1 receptor antagonist. |
|---|---|
| Related Catalog | |
| Target |
Histamine H1-receptor[1] |
| In Vitro | Mebhydrolin is a specific histamine H1-receptor antagonist with minimal sedative properties and comparing it with the effects of chlorpromazine, the archetypical phenothiazine[1]. Mebhydrolin exerts an antihistaminic effect over the period of the ethanol interaction study[2]. |
| References |
| Density | 1.12 g/cm3 |
|---|---|
| Boiling Point | 856.1ºC at 760 mmHg |
| Molecular Formula | C19H20N2 |
| Molecular Weight | 276.37600 |
| Flash Point | 471.6ºC |
| Exact Mass | 276.16300 |
| PSA | 8.17000 |
| LogP | 3.61540 |
| Index of Refraction | 1.633 |
| Storage condition | 2-8℃ |
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524-81-2 |
| Literature: Yutilov; Smolyar; Volchkov Pharmaceutical Chemistry Journal, 2000 , vol. 34, # 12 p. 661 - 662 |
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524-81-2 |
| Literature: Yutilov; Smolyar; Volchkov Pharmaceutical Chemistry Journal, 2000 , vol. 34, # 12 p. 661 - 662 |
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524-81-2 |
| Literature: Farbenfabr. Bayer Patent: DE930444 , 1951 ; Full Text Show Details Schenley Ind. Patent: US2786059 , 1954 ; Full Text Show Details Hoerlein Chemische Berichte, 1954 , vol. 87, p. 463,467, 470 |
| Precursor 4 | |
|---|---|
| DownStream 0 | |