- Shanghai Nianxing Industrial Co., Ltd
- China
- Product Name: 6,7,8-Trimethoxycoumarin
- Price: Check
- Purity: 98.0%
- Stocking Period: 10 Day
- Contact: Yang
- Email: sales@echemcloud.com
- Shanghai Jizhi Biochemical Technology Co., Ltd
- China
- Product Name: 6,7,8-Trimethoxycoumarin
- Price: ￥1478.0/20mg
- Purity: 98.0%
- Stocking Period: 1 Day
- Contact: Liu jia
- Email: 2130147988@qq.com
- DC Chemicals Limited
- China
- Product Name: Dimethylfraxetin
- Price: $280.0/20mg
- Purity: 98.0%
- Stocking Period: 3 Day
- Contact: Tony Cao
- Email: sales@dcchemicals.com
- Dayang Chem (Hangzhou) Co., Ltd.
- China
- Product Name: 6,7,8-Trimethoxycoumarin
- Price: $Inquiry/100g $Inquiry/1kg $Inquiry/100kg $Inquiry/1000kg
- Purity: 98.0%
- Stocking Period: Inquiry
- Contact: Ms Wang
- Email: enquiry@dycnchem.com
6035-49-0
6035-49-0 structure
- Name: 6,7,8-Trimethoxycoumarin
- Chemical Name: Dimethylfraxetin
- CAS Number: 6035-49-0
- Molecular Formula: C12H12O5
- Molecular Weight: 236.221
- Catalog: Pharmaceutical intermediate Heterocyclic compound Pyran compound
- Create Date: 2018-03-21 08:00:00
- Modify Date: 2025-08-21 21:40:04
-
Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a Ki value of 0.0097 μM.
| Name | Dimethylfraxetin |
|---|---|
| Synonyms |
6,7,8-trimethoxychromen-2-one
6,7,8-Trimethoxy-2H-chromen-2-one 2H-1-Benzopyran-2-one, 6,7,8-trimethoxy- |
| Description | Dimethylfraxetin is a Carbonic anhydrase inhibitor, with a Ki value of 0.0097 μM. |
|---|---|
| Related Catalog | |
| Target |
Ki: 0.0097 μM (Carbonic anhydrase)[1] |
| In Vitro | At CA I there is one stand out compound being Dimethylfraxetin (compound 17), a nanomolar CA I inhibitor. This trimethoxy coumarin is the most potent of any of the NP coumarins across the six CA isozymes of the present study[1]. |
| Kinase Assay | Inhibitor (including Dimethylfraxetin) and enzyme solutions are preincubated together for 6 h at room temperature prior to assay, in order to allow for the formation of the enzyme-inhibitor complex[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 408.0±45.0 °C at 760 mmHg |
| Melting Point | 104-105ºC |
| Molecular Formula | C12H12O5 |
| Molecular Weight | 236.221 |
| Flash Point | 184.3±28.8 °C |
| Exact Mass | 236.068466 |
| PSA | 57.90000 |
| LogP | 1.75 |
| Vapour Pressure | 0.0±1.0 mmHg at 25°C |
| Index of Refraction | 1.545 |
| Storage condition | -20°C |
| Precursor 10 | |
|---|---|
| DownStream 1 | |
| HS Code | 2932209090 |
|---|---|
| Summary | 2932209090. other lactones. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0% |