Top Suppliers:I want be here


85081-69-2

85081-69-2 structure
85081-69-2 structure
  • Name: TCO-OH
  • Chemical Name: 4-Cycloocten-1-ol, (4E)
  • CAS Number: 85081-69-2
  • Molecular Formula: C8H14O
  • Molecular Weight: 126.19600
  • Catalog: Signaling Pathways PROTAC PROTAC Linker
  • Create Date: 2017-10-13 11:43:27
  • Modify Date: 2025-08-26 18:28:08
  • TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].

Name 4-Cycloocten-1-ol, (4E)
Synonyms (E)-CYCLOOCT-4-ENOL
4-Cycloocten-1-ol, (E)-
(E)-Cyclooct-4-enol
Description TCO-OH is an alkyl chain-based PROTAC linker that can be used in the synthesis of PROTACs[1].
Related Catalog
Target

Alkyl-Chain

In Vitro PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].
References

[1]. An S, et al. Small-molecule PROTACs: An emerging and promising approach for the development of targeted therapy drugs. EBioMedicine. 2018 Oct;36:553-562.

Molecular Formula C8H14O
Molecular Weight 126.19600
Exact Mass 126.10400
PSA 20.23000
LogP 1.86760
Storage condition 20°C
Symbol GHS05
GHS05
Signal Word Danger
Hazard Statements H318
Precautionary Statements P280-P305 + P351 + P338
Hazard Codes C
Risk Phrases 41-52
Safety Phrases 26-39
RIDADR NONH for all modes of transport
The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.