28178-92-9
28178-92-9 structure
- Name: Futoquinol
- Chemical Name: 4-[(E)-1-(1,3-benzodioxol-5-yl)prop-1-en-2-yl]-4,5-dimethoxy-2-prop-2-enylcyclohexa-2,5-dien-1-one
- CAS Number: 28178-92-9
- Molecular Formula: C21H22O5
- Molecular Weight: 354.396
- Catalog: Natural product Lignans
- Create Date: 2018-09-07 12:24:33
- Modify Date: 2025-08-25 18:14:38
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Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities[1].
| Name | 4-[(E)-1-(1,3-benzodioxol-5-yl)prop-1-en-2-yl]-4,5-dimethoxy-2-prop-2-enylcyclohexa-2,5-dien-1-one |
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| Synonyms |
2-Allyl-4-[(1E)-1-(1,3-benzodioxol-5-yl)-1-propen-2-yl]-4,5-dimethoxy-2,5-cyclohexadien-1-one
2-Allyl-4-[(E)-2-(1,3-benzodioxol-5-yl)-1-methylethenyl]-4,5-dimethoxy-2,5-cyclohexadien-1-one (E)-2-Allyl-4-(2-(1,3-benzodioxol-5-yl)-1-methylvinyl)-4,5-dimethoxy-2,5-cyclohexadien-1-one 2,5-Cyclohexadien-1-one, 4-[(E)-2-(1,3-benzodioxol-5-yl)-1-methylethenyl]-4,5-dimethoxy-2-(2-propen-1-yl)- Futoquinol |
| Description | Futoquinol is a neolignan isolated from the dried aerial parts of Piper kadsura (Piperaceae). Futoquinol potently inhibits NO production in microglia cells. Futoquinol has anti-neuroinflammatory activities[1]. |
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| Related Catalog | |
| In Vitro | Futoquinol potently inhibits NO production with an IC50 value of 16.8 μM in LPS-activated BV-2 cells, a microglia cell line[1]. |
| References |
| Density | 1.2±0.1 g/cm3 |
|---|---|
| Boiling Point | 515.0±50.0 °C at 760 mmHg |
| Molecular Formula | C21H22O5 |
| Molecular Weight | 354.396 |
| Flash Point | 225.5±30.2 °C |
| Exact Mass | 354.146729 |
| PSA | 53.99000 |
| LogP | 4.82 |
| Vapour Pressure | 0.0±1.3 mmHg at 25°C |
| Index of Refraction | 1.582 |
| Hazard Codes | Xi |
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