860642-69-9

860642-69-9 structure

Name: Serlopitant
Chemical Name: 3-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]cyclopent-2-en-1-one
CAS Number: 860642-69-9
Molecular Formula: C₂₉H₂₈F₇NO₂
Molecular Weight: 555.52700
Catalog: Signaling Pathways GPCR/G Protein Neurokinin Receptor
Create Date: 2017-09-21 00:48:44
Modify Date: 2025-08-25 22:56:00
Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.

Name	3-[(3aR,4R,5S,7aS)-5-[(1R)-1-[3,5-bis(trifluoromethyl)phenyl]ethoxy]-4-(4-fluorophenyl)-1,3,3a,4,5,6,7,7a-octahydroisoindol-2-yl]cyclopent-2-en-1-one
Synonyms	UNII-277V92K32B Serlopitant

Description	Serlopitant is a selective Neurokinin-1 (NK-1) receptor antagonist.
Related Catalog	Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor Research Areas >> Neurological Disease
Target	Neurokinin-1 receptor[1]
References	[1]. Yosipovitch G, et al. Serlopitant for the treatment of chronic pruritus: Results of a randomized, multicenter, placebo-controlled phase 2 clinical trial. J Am Acad Dermatol. 2018 May;78(5):882-891.