158493-17-5

158493-17-5 structure

Name: MK 386
Chemical Name: 4,6,9a,11a-tetramethyl-1-(6-methylheptan-2-yl)-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-7-one
CAS Number: 158493-17-5
Molecular Formula: C₂₈H₄₉NO
Molecular Weight: 415.69
Catalog: Signaling Pathways Metabolic Enzyme/Protease 5 alpha Reductase
Create Date: 2016-06-25 11:40:51
Modify Date: 2025-08-28 08:17:56
MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].

Name	4,6,9a,11a-tetramethyl-1-(6-methylheptan-2-yl)-2,3,3a,3b,4,5,5a,8,9,9b,10,11-dodecahydro-1H-indeno[5,4-f]quinolin-7-one

Description	MK 386 (L-733692) is a selective 5-α-reductase I inhibitor, used for prostate cancer inhibition[1].
Related Catalog	Research Areas >> Cancer Signaling Pathways >> Metabolic Enzyme/Protease >> 5 alpha Reductase
Target	5-α-reductase I[1]
References	[1]. Bühler P, et al. Comparison of gene expression in LNCaP prostate cancer cells after treatment with bicalutamide or 5-alpha-reductase inhibitors. Urol Int. 2010;84(2):203-11.