1356962-20-3
1356962-20-3 structure
- Name: AZD-3463
- Chemical Name: N-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine
- CAS Number: 1356962-20-3
- Molecular Formula: C24H25ClN6O
- Molecular Weight: 448.948
- Catalog: Biochemical Inhibitor Protein tyrosine kinase
- Create Date: 2017-03-25 15:43:42
- Modify Date: 2025-08-22 21:53:52
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AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib.IC50 Value:Target: ALK/IGF1R
| Name | N-[4-(4-aminopiperidin-1-yl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine |
|---|---|
| Synonyms |
ALK/IGF1R inhibitor||AZD3463|AZD 3463
N-[4-(4-Amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)-2-pyrimidinamine AZD3463 2-Pyrimidinamine, N-[4-(4-amino-1-piperidinyl)-2-methoxyphenyl]-5-chloro-4-(1H-indol-3-yl)- ALK/IGF1R inhibitor S7106 N-(4-(4-aminopiperidin-1-yl)-2-methoxyphenyl)-5-chloro-4-(1H-indol-3-yl)pyrimidin-2-amine CS-1382 AZD-3463 |
| Description | AZD-3463 is an ALK/IGF1R inhibitor which overcomes multiple mechanisms of acquired resistance to crizotinib.IC50 Value:Target: ALK/IGF1R |
|---|---|
| Related Catalog |
| Density | 1.3±0.1 g/cm3 |
|---|---|
| Boiling Point | 723.6±70.0 °C at 760 mmHg |
| Molecular Formula | C24H25ClN6O |
| Molecular Weight | 448.948 |
| Flash Point | 391.4±35.7 °C |
| Exact Mass | 448.177826 |
| PSA | 92.09000 |
| LogP | 3.11 |
| Vapour Pressure | 0.0±2.3 mmHg at 25°C |
| Index of Refraction | 1.693 |
| Storage condition | -20℃ |
| Precursor 2 | |
|---|---|
| DownStream 0 | |
