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52940-48-4

52940-48-4 structure
52940-48-4 structure
  • Name: 9H-Purine,6-(4-morpholinyl)-9-b-D-ribofuranosyl-
  • Chemical Name: 2-(hydroxymethyl)-5-(6-morpholin-4-ylpurin-9-yl)oxolane-3,4-diol
  • CAS Number: 52940-48-4
  • Molecular Formula: C14H19N5O5
  • Molecular Weight: 337.33
  • Catalog: Signaling Pathways Cell Cycle/DNA Damage Nucleoside Antimetabolite/Analog
  • Create Date: 2016-05-08 14:01:54
  • Modify Date: 2025-08-26 19:41:35
  • 6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Name 2-(hydroxymethyl)-5-(6-morpholin-4-ylpurin-9-yl)oxolane-3,4-diol
Synonyms 6-(morpholin-4-yl)-9-pentofuranosyl-9H-purine
6-morpholinopurine riboside
Description 6-(4-Morpholinyl)-9-β-D-ribofuranosyl-9H-purine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].
Related Catalog
References

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Density 1.82g/cm3
Boiling Point 684.9ºC at 760 mmHg
Molecular Formula C14H19N5O5
Molecular Weight 337.33
Flash Point 368ºC
Exact Mass 337.13900
PSA 125.99000
Index of Refraction 1.805
110-91-8 structure

110-91-8

927818-53-9 structure

927818-53-9

~58%

52940-48-4 structure

52940-48-4

Literature: Bae, Suyeal; Lakshman, Mahesh K. Journal of the American Chemical Society, 2009 , vol. 131, # 49 p. 17993 - 17993
58-63-9 structure

58-63-9

~%

52940-48-4 structure

52940-48-4

Literature: Bae, Suyeal; Lakshman, Mahesh K. Journal of the American Chemical Society, 2007 , vol. 129, # 4 p. 782 - 789
385806-18-8 structure

385806-18-8

~%

52940-48-4 structure

52940-48-4

Literature: Lin, Xiaoyu; Robins, Morris J. Organic Letters, 2000 , vol. 2, # 22 p. 3497 - 3499
3181-38-2 structure

3181-38-2

~%

52940-48-4 structure

52940-48-4

Literature: Lin, Xiaoyu; Robins, Morris J. Organic Letters, 2000 , vol. 2, # 22 p. 3497 - 3499
110-91-8 structure

110-91-8

2004-06-0 structure

2004-06-0

~%

52940-48-4 structure

52940-48-4

Literature: Kikugawa,K. et al. Journal of Medicinal Chemistry, 1972 , vol. 15, p. 387 - 390
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