Dayang Chem (Hangzhou) Co., Ltd.
China
Product Name: D-Mannitol,1,6-dimethanesulfonate
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Purity: 98.0%
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1187-00-4

1187-00-4 structure

1187-00-4 structure

Name: D-Mannitol,1,6-dimethanesulfonate
Chemical Name: D-Mannitol,1,6-dimethanesulfonate
CAS Number: 1187-00-4
Molecular Formula: C₈H₁₈O₁₀S₂
Molecular Weight: 338.35300
Create Date: 2016-07-01 01:03:09
Modify Date: 2024-01-11 22:32:26

Name	D-Mannitol,1,6-dimethanesulfonate
Synonyms	O1,O6-Dimethansulfonyl-D-mannit Mannogranol D-Mannitol busulphan D-Mannitol busulfan O1,O6-bis-methanesulfonyl-D-mannitol 1,6-Bis-methansulfonyl-D-mannit MANNITOL,1,6-DIMETHYLSULPHONATE,D 1,6-Di-O-methansulfonyl-D-mannitol 2511 C. B. O1,O6-Bis-methansulfonyl-D-mannit 1,6-Dimethanesulfonate-D-mannitol 1,6-Bis-methansulfonyloxy-D-manno-hexan-2,3,4,5-tetraol 1,6-Dimesyl-D-mannitol 1,6-Di-O-methansulfonyl-D-mannit 1,6-Dimethanesulfonoxy-D-mannitol

Density	1.635g/cm3
Boiling Point	721.3ºC at 760 mmHg
Melting Point	134-136 °C
Molecular Formula	C₈H₁₈O₁₀S₂
Molecular Weight	338.35300
Flash Point	390ºC
Exact Mass	338.03400
PSA	184.42000
Vapour Pressure	5.01E-24mmHg at 25°C
Index of Refraction	1.553

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OP2975000

CHEMICAL NAME :: Mannitol, 1,6-dimethanesulfonate, D-

CAS REGISTRY NUMBER :: 1187-00-4

LAST UPDATED :: 199707

DATA ITEMS CITED :: 12

MOLECULAR FORMULA :: C8-H18-O10-S2

MOLECULAR WEIGHT :: 338.38

WISWESSER LINE NOTATION :: WS1&O1YQYQYQYQ1OSW1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 2 gm/kg

TOXIC EFFECTS :: Blood - normocytic anemia Blood - thrombocytopenia

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 6 gm/kg

TOXIC EFFECTS :: Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 2500 mg/kg

TOXIC EFFECTS :: Tumorigenic - protects against induction of experimental tumors

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Mammal - dog

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - agranulocytosis Blood - other changes

TYPE OF TEST :: LDLo - Lowest published lethal dose

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Primate - monkey

DOSE/DURATION :: 135 mg/kg

TOXIC EFFECTS :: Blood - leukopenia Blood - agranulocytosis Blood - other changes

TYPE OF TEST :: TDLo - Lowest published toxic dose

ROUTE OF EXPOSURE :: Intraperitoneal

SPECIES OBSERVED :: Rodent - mouse

DOSE/DURATION :: 1000 mg/kg/4W

TOXIC EFFECTS :: Tumorigenic - neoplastic by RTECS criteria Lungs, Thorax, or Respiration - tumors

TYPE OF TEST :: Specific locus test

TYPE OF TEST :: Cytogenetic analysis

TYPE OF TEST :: Sex chromosome loss and nondisjunction

TYPE OF TEST :: Sex chromosome loss and nondisjunction

MUTATION DATA

TYPE OF TEST :: DNA inhibition

TEST SYSTEM :: Rodent - rabbit Bone marrow

DOSE/DURATION :: 1700 umol/L

REFERENCE :: BCPCA6 Biochemical Pharmacology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.1- 1958- Volume(issue)/page/year: 25,1705,1976

HS Code	2905499000

HS Code	2905499000
Summary	2905499000 other polyhydric alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%