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6286-09-5

6286-09-5 structure
6286-09-5 structure
  • Name: NSC10010 hydrochloride
  • Chemical Name: N,N-Bis(2-methyl-6-methoxy-4-quinaldyl)-1,9-diamino- nonane Dihydrochloride Hydrate
  • CAS Number: 6286-09-5
  • Molecular Formula: C31H41ClN4O2
  • Molecular Weight: 537.13600
  • Catalog: Signaling Pathways Anti-infection Bacterial
  • Create Date: 2017-07-04 05:21:13
  • Modify Date: 2024-04-09 12:39:47
  • NSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase[1][2].

Name N,N-Bis(2-methyl-6-methoxy-4-quinaldyl)-1,9-diamino- nonane Dihydrochloride Hydrate
Description NSC10010 hydrochloride inhibits gammaherpesvirus associated B-lymphomas growth through activation of NF-kB and c-Myc-mediated signaling pathways. NSC10010 hydrochloride induces necrotic cell death in gammaherpesvirus infected B-cells. NSC10010 hydrochloride is also an inhibitor of Mtb ClpC1 ATPase[1][2].
Related Catalog
References

[1]. Dzeng RK, et al. Small molecule growth inhibitors of human oncogenic gammaherpesvirus infected B-cells. Mol Oncol. 2015 Feb;9(2):365-76.  

[2]. Amritansh Bhanot, et al. Discovery of small molecule inhibitors of Mycobacterium tuberculosis ClpC1: SAR studies and antimycobacterial evaluation. Results in Chemistry. Volume 5, January 2023, 100904.

Density 1.137g/cm3
Boiling Point 674.2ºC at 760 mmHg
Molecular Formula C31H41ClN4O2
Molecular Weight 537.13600
Flash Point 361.5ºC
Exact Mass 536.29200
PSA 68.30000
LogP 8.61970
Index of Refraction 1.632
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