65182-56-1

65182-56-1 structure

Name: 3-amino-2-chloro-6-(trifluoromethyl)pyridine
Chemical Name: 6-(1H-1,8-naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one
CAS Number: 65182-56-1
Molecular Formula: C₁₄H₁₀N₂O
Molecular Weight: 222.24200
Catalog: Pharmaceutical intermediate Heterocyclic compound Pyridine compound Methylpyridine
Create Date: 2018-12-26 13:47:36
Modify Date: 2024-01-14 17:19:45
2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells[1].

Name	6-(1H-1,8-naphthyridin-2-ylidene)cyclohexa-2,4-dien-1-one
Synonyms	2-<o-Hydroxy-phenyl>-1,8-naphthyridin

Description	2-NP is a selective enhancer of STAT1 transcription. 2-NP can enhance the ability of IFN-γ to inhibit the proliferation of human breast cancer and fibrosarcoma cells[1].
Related Catalog	Signaling Pathways >> Stem Cell/Wnt >> STAT Research Areas >> Cancer Signaling Pathways >> JAK/STAT Signaling >> STAT
References	[1]. Lynch RA, et, al. A small-molecule enhancer of signal transducer and activator of transcription 1 transcriptional activity accentuates the antiproliferative effects of IFN-gamma in human cancer cells. Cancer Res. 2007 Feb 1;67(3):1254-61.

Symbol	GHS05, GHS07
Signal Word	Danger
Hazard Statements	H302-H318
Precautionary Statements	P280-P305 + P351 + P338
Hazard Codes	Xn,T
Risk Phrases	22-41-36-25
Safety Phrases	26-39-45
RIDADR	NONH for all modes of transport
HS Code	2933990090

HS Code	2933990090
Summary	2933990090. heterocyclic compounds with nitrogen hetero-atom(s) only. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:20.0%