esatenolol

Names

[ Name ]:
esatenolol

[Synonym ]:
(-)-4-[2-hydroxy-3-[(1-methylethyl)amino]propoxy]benzeneacetamide
S-(-)-Atenolol
(S)-4-[2-hydroxy-3-((1-methylethyl)amino)propoxy]benzeneacetamide
MFCD00074918
(-)-Atenolol
1-Phenylbiguanide hydrochloride
2-[4-[(2S)-2-hydroxy-3-(propan-2-ylamino)propoxy]phenyl]acetamide
Esatenolol [INN]
4-{(2S)-2-hydroxy-3-[(1-methylethyl)amino]propoxy}benzeneacetamide
Esatenolol

Chemical & Physical Properties

[ Density]:
1.125 g/cm3

[ Boiling Point ]:
508ºC at 760mmHg

[ Melting Point ]:
148-152 ºC(lit.)

[ Molecular Formula ]:
C₁₄H₂₂N₂O₃

[ Molecular Weight ]:
266.33600

[ Flash Point ]:
261.1ºC

[ Exact Mass ]:
266.16300

[ PSA ]:
84.58000

[ LogP ]:
1.54330

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: CY1488020

CHEMICAL NAME :: Benzeneacetamide, 4-(2-hydroxy-3-((1-methylethyl)amino)propoxy)-, (S)-

CAS REGISTRY NUMBER :: 93379-54-5

LAST UPDATED :: 199403

DATA ITEMS CITED :: 1

MOLECULAR FORMULA :: C14-H22-N2-O3

MOLECULAR WEIGHT :: 266.38

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Intravenous

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 97 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

REFERENCE :: PIXXD2 PCT (Patent Cooperation Treaty) International Application. (U.S. Patent and Trademark Office, Foreign Patents, Washington, DC 20231) Volume(issue)/page/year: #91-10428

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ RTECS ]:
CY1488020

[ HS Code ]:
2924299090

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 2924299090

[ Summary ]:
2924299090. other cyclic amides (including cyclic carbamates) and their derivatives; salts thereof. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:30.0%

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