(R)-Alcohol dehydrogenase

Names

[ Name ]:
(R)-Alcohol dehydrogenase

[Synonym ]:
1H-Indole-3-propanamide, N-[3-[[3-[(6-chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl]methylamino]propyl]-
N-{3-[{3-[(6-Chloro-1,2,3,4-tetrahydro-9-acridinyl)amino]propyl}(methyl)amino]propyl}-3-(1H-indol-3-yl)propanamide
N-{3-[{3-[(6-chloro-1,2,3,4-tetrahydroacridin-9-yl)amino]propyl}(methyl)amino]propyl}-3-(1H-indol-3-yl)propanamide

Biological Activity

[Description]:

(R)-Alcohol dehydrogenase (E.C. 1.1.1.2) is a biochemical reagent that can be used as a biological material or organic compound for life science related research.

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
806.8±65.0 °C at 760 mmHg

[ Molecular Formula ]:
C₃₁H₃₈ClN₅O

[ Molecular Weight ]:
532.119

[ Flash Point ]:
441.7±34.3 °C

[ Exact Mass ]:
531.276489

[ LogP ]:
5.89

[ Vapour Pressure ]:
0.0±2.9 mmHg at 25°C

[ Index of Refraction ]:
1.663

Safety Information

[ Symbol ]:

GHS08

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H317-H334

[ Precautionary Statements ]:
P261-P280-P342 + P311

[ Personal Protective Equipment ]:
Eyeshields;Gloves

[ Hazard Codes ]:
Xn

[ Risk Phrases ]:
42/43

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

Articles

Efficient one-step production of (S)-1-phenyl-1,2-ethanediol from (R)-enantiomer plus NAD(+)-NADPH in-situ regeneration using engineered Escherichia coli.

Microb. Cell Fact. 11 , 167, (2012)

Candida parapsilosis CCTCC M203011 catalyzes the stereoinversion of (R)-1-phenyl-1,2-ethanediol (PED) through oxidation and reduction. Its NAD(+)-linked (R)-carbonyl reductase (RCR) catalyzes the oxid...

A new strategy to improve the efficiency and sustainability of Candida parapsilosis catalyzing deracemization of (R,S)-1-phenyl-1,2-ethanediol under non-growing conditions: increase of NADPH availability.

J. Microbiol. Biotechnol. 19(1) , 65-71, (2009)

Microbial oxidoreductive systems have been widely used in asymmetric syntheses of optically active alcohols. However, when reused in multi-batch reaction, the catalytic efficiency and sustainability o...

Stereospecificity of ketoreductase domains 1 and 2 of the tylactone modular polyketide synthase.

J. Am. Chem. Soc. 130 , 11598-11599, (2008)

Tylactone synthase (TYLS) is a modular polyketide synthase that catalyzes the formation of tylactone (1), the parent aglycone precursor of the macrolide antibiotic tylosin. TYLS modules 1 and 2 are re...