Ortho-hydroxy atorvastatin lactone-d5
Names
[ CAS No. ]:
265989-50-2
[ Name ]:
Ortho-hydroxy atorvastatin lactone-d5
[Synonym ]:
2-Hydroxy Atorvastatin Lactone-d5
Biological Activity
[Description]:
Ortho-hydroxy atorvastatin lactone-d5 is deuterium labeled 2-Hydroxy atorvastatin lactone. 2-Hydroxy atorvastatin lactone is a metabolite of Atorvastatin. Atorvastatin is an orally active HMG-CoA reductase inhibitor, has the ability to effectively decrease blood lipids[1][2].
[Related Catalog]:
[In Vitro]
Stable heavy isotopes of hydrogen, carbon, and other elements have been incorporated into drug molecules, largely as tracers for quantitation during the drug development process. Deuteration has gained attention because of its potential to affect the pharmacokinetic and metabolic profiles of drugs[1].
[References]
Chemical & Physical Properties
[ Molecular Formula ]:
C33H28D5FN2O5
[ Molecular Weight ]:
561.65
[ Exact Mass ]:
561.26900
[ PSA ]:
104.28000
[ LogP ]:
6.88310