HCAIX-IN-2

Names

[ CAS No. ]:
2389034-45-9

[ Name ]:
HCAIX-IN-2

Biological Activity

[Description]:

HCAIX-IN-2 (compound 9d) is a selective carbonic anhydrase inhibitor with the Ki values of 24.6 nM and 45.3 nM for hCA IX and hCA XII, respectively[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Metabolic Enzyme/Protease >> Carbonic Anhydrase

[Target]

CA I:2481 nM (Ki)

hCA II:456.2 nM (Ki)

hCA IX:24.6 nM (Ki)

hCA XII:45.3 nM (Ki)


[References]

[1]. Mohamed A Said, et al. Synthesis, biological and molecular dynamics investigations with a series of triazolopyrimidine/triazole-based benzenesulfonamides as novel carbonic anhydrase inhibitors. Eur J Med Chem. 2020 Jan 1;185:111843.

Chemical & Physical Properties

[ Molecular Formula ]:
C19H16N8O4S

[ Molecular Weight ]:
452.45

Related Compounds

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