Amidate-VC-PAB-MMAF

Names

[ CAS No. ]:
2202782-90-7

[ Name ]:
Amidate-VC-PAB-MMAF

Biological Activity

[Description]:

Amidate-VC-PAB-MMAF consists a cleavable ADC linker (Amidate-VC-PAB) and a potent tubulin polymerization inhibitor (MMAF). Amidate-VC-PAB-MMAF can be used in the synthesis of antibody-drug conjugates (ADCs). Amidate-VC-PAB-MMAF reduces off-target cytotoxicity of ADCs[1].

[Related Catalog]:

Research Areas >> Cancer

[References]

[1]. Nareshkumar Jain, et al. Current ADC Linker Chemistry. Pharm Res. 2015 Nov;32(11):3526-40.

Chemical & Physical Properties

[ Molecular Formula ]:
C₆₉H₁₀₂N₁₁O₁₆P

[ Molecular Weight ]:
1372.59

Related Compounds

The content on this webpage is sourced from various professional data sources. If you have any questions or concerns regarding the content, please feel free to contact service1@chemsrc.com.