Amyloid β-Protein (1-40) (mouse, rat)
Names
[ CAS No. ]:
144409-98-3
[ Name ]:
Amyloid β-Protein (1-40) (mouse, rat)
[Synonym ]:
AMyloid b-Protein (1-40) (Mouse, rat)
Rat aMyloid-β peptide 1-40
Amyloid beta-peptide (1-40) (rat)
Amyloid β-peptide (1-40) (rat)
Rat aMyloid-beta peptide 1-40
H-Asp-Ala-Glu-Phe-Gly-His-Asp-Ser-Gly-Phe-Glu-Val-Arg-His-Gln-Lys-Leu-Val-Phe-Phe-Ala-Glu-Asp-Val-Gly-Ser-Asn-Lys-Gly-Ala-Ile-Ile-Gly-Leu-Met-Val-Gly-Gly-Val-Val-OH
Biological Activity
[Description]:
[Related Catalog]:
[Target]
The Amyloid β-peptide (1-40) (rat)-treated rats require longer to find the platform hidden under the water. In the visible platform test, the latency for each group is similar (20.56±11.31 s in control and 14.68±9.97 s in Amyloid β-peptide (1-40) (rat) group, p=0.304). Among these tested proteins, 6 ones are significantly up-regulated and 7 ones significantly down-regulated in Amyloid β-peptide (1-40) (rat) group comparing with the control. Tubulin β chain is significantly down-regulated in Amyloid β-peptide (1-40) (rat) group (p=0.014) when compare with control. Similar changes are also observed for ATP synthase β subunit (p=0.010) and synapsin Ib between Amyloid β-peptide (1-40) (rat) and control groups, but not significantly for synapsin Ib (p=0.295)[1].
[Animal admin]
[References]
[Related Small Molecules]
Chemical & Physical Properties
[ Molecular Formula ]:
C190H291N51O57S
[ Molecular Weight ]:
4233.778
[ Exact Mass ]:
4233.123