nips hcl
Names
Chemical & Physical Properties
[ Density]:
1.22g/cm3
[ Boiling Point ]:
754.7ºC at 760mmHg
[ Molecular Formula ]:
C32H34ClFN4O2S
[ Molecular Weight ]:
593.15400
[ Flash Point ]:
410.2ºC
[ Exact Mass ]:
592.20800
[ PSA ]:
88.31000
[ LogP ]:
6.64930
[ Vapour Pressure ]:
1.15E-22mmHg at 25°C
[ Index of Refraction ]:
1.632
Safety Information
Articles
Mol. Pharmacol. 42 , 856-863, (1992)
Alkyl and arylalkyl derivatives of the dopamine (DA) D2 antagonist spiperone were prepared and characterized chemically and pharmacologically. They included the N-methyl, N-phenethyl (NPS), and N-p-am...
N-(p-isothiocyanatophenethyl)spiperone, a selective and irreversible antagonist of D2 dopamine receptors in brain.J. Pharmacol. Exp. Ther. 257 , 608-615, (1991)
N-ethoxycarbonyl-2-ethoxy-1,2-dihydroquinoline (EEDQ), an irreversible and nonselective protein-modifying reagent, has been used extensively in studies involving inactivation of receptors. Here, we pr...
Modulation of [(35)S]GTPgammaS binding to chinese hamster ovary cell membranes by D(2(short)) dopamine receptors.Neurosci. Lett. 280(2) , 135-8, (2000)
Rat dopamine D(2short) expressed in Chinese hamster ovary (CHO) cells were characterized by means of activation of [(35)S]-guanosine 5'-O-(gamma-thiotriphosphate) ([(35)S]GTPgammaS) binding and inhibi...