3’-Deoxy-3’-fluoro-5-methyluridine

Names

[ CAS No. ]:
125217-37-0

[ Name ]:
3’-Deoxy-3’-fluoro-5-methyluridine

[Synonym ]:
3'-Deoxy-3'-fluoro-5-methyluridine
MFCD27921028
1-(3-Deoxy-3-fluoro-β-D-ribofuranosyl)thymine
Uridine, 3'-deoxy-3'-fluoro-5-methyl-

Biological Activity

[Description]:

3’-Deoxy-3’-fluoro-5-methyluridine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Density]:
1.6±0.1 g/cm3

[ Molecular Formula ]:
C10H13FN2O5

[ Molecular Weight ]:
260.22

[ Exact Mass ]:
260.080841

[ LogP ]:
-0.59

[ Index of Refraction ]:
1.593

Related Compounds

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