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[Sar9] Substance P

Names

[ CAS No. ]:
77128-75-7

[ Name ]:
[Sar9] Substance P

[Synonym ]:
L-Arg-L-Pro-L-Lys-L-Pro-L-Glu(NH2)-L-Glu(NH2)-L-Phe-L-Phe-Sar-L-Leu-L-Met-NH2
L-Arg-L-Pro-L-Lys-L-Pro-L-Gln-L-Gln-L-Phe-L-Phe-Sar-L-Leu-L-Met-NH2
H-Arg-Pro-Lys-Pro-Gln-Gln-Phe-Phe-Sar-Leu-Met-NH2
Substance P,[Sar9]
9-(N-METHYLGLYCINE)SUBSTANCE P)
[SAR9]-SUBSTANCE P
[Sar9] Substance P

Biological Activity

[Description]:

[Sar9] Substance P is a potent and selective neurokinin (NK)-1 receptor agonist[1].

[Related Catalog]:

Signaling Pathways >> Neuronal Signaling >> Neurokinin Receptor
Research Areas >> Neurological Disease
Signaling Pathways >> GPCR/G Protein >> Neurokinin Receptor

[Target]

Neurokinin (NK)-1 receptor[1]


[References]

[1]. Lieberman DN, et al. Substance P enhances NMDA channel function in hippocampal dentate gyrus granule cells. J Neurophysiol. 1998 Jul;80(1):113-9.

Chemical & Physical Properties

[ Molecular Formula ]:
C64H100N18O13S

[ Molecular Weight ]:
1361.66

[ Exact Mass ]:
1360.74000

[ PSA ]:
533.14000

[ LogP ]:
4.14540

Safety Information

[ WGK Germany ]:
3


Related Compounds