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Peimisine

Names

[ CAS No. ]:
19773-24-1

[ Name ]:
Peimisine

[Synonym ]:
(3β,5α,17β,22S,23R)-3-Hydroxy-5,6-dihydro-17,23-epoxyveratraman-6-one
Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-5(6H)-one, 1,2,3,3'a,4,4',4a,5',6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (3S,3'R,3a'S,6'S,6aR,6bS,9R,11aS,11bR)-
Veratraman-6(5H)-one, 17,23-epoxy-3-hydroxy-, (3β)-
Spiro[9H-benzo[a]fluorene-9,2'(3'H)-furo[3,2-b]pyridin]-5(6H)-one, 1,2,3,3'a,4,4',4a,5',6',6a,6b,7,7',7'a,8,11,11a,11b-octadecahydro-3-hydroxy-3',6',10,11b-tetramethyl-, (3S,3'R,3a'S,4aS,6'S,6aR,6bS,7a'R,9R,11aS,11bR)-
(3β,22S)-3-Hydroxy-5,6-dihydro-17,23-epoxyveratraman-6-one
Veratraman-6(5H)-one, 17,23-epoxy-3-hydroxy-, (3β,5α,23β)-
(3β,5α,22S,23R)-3-Hydroxy-5,6-dihydro-17,23-epoxyveratraman-6-one

Biological Activity

[Description]:

Peimisine(Ebeiensine) is a steroidal alkaloid which is the major biologically active component in Bulbus Fritillariae; possess a variety of toxicological and pharmacological effects on humans.

[Related Catalog]:

Signaling Pathways >> Others >> Others
Natural Products >> Alkaloid
Research Areas >> Others

[References]

[1]. Pan F, et al. Peimisine and peiminine production by endophytic fungus Fusarium sp. isolated from Fritillaria unibracteata var. wabensis. Phytomedicine. 2014 Jul-Aug;21(8-9):1104-9.


[Related Small Molecules]

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Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Boiling Point ]:
573.0±50.0 °C at 760 mmHg

[ Melting Point ]:
270℃

[ Molecular Formula ]:
C27H41NO3

[ Molecular Weight ]:
427.619

[ Flash Point ]:
300.3±30.1 °C

[ Exact Mass ]:
427.308655

[ PSA ]:
58.56000

[ LogP ]:
3.70

[ Vapour Pressure ]:
0.0±3.6 mmHg at 25°C

[ Index of Refraction ]:
1.578

[ Storage condition ]:
-20°C

Safety Information

[ Safety Phrases ]:
24/25


Related Compounds