Collagen

Names

[ Name ]:
Collagen

[Synonym ]:
MFCD00130825
Alanine, N-[[1-[2-[(2-aminopropyl)amino]acetyl]-2-pyrrolidinyl]hydroxymethylene]-
N-[{1-[N-(2-Aminopropyl)glycyl]-2-pyrrolidinyl}(hydroxy)methylene]alanine

Biological Activity

[Description]:

Collagens are extracellular matrix proteins and show many applications in food, cosmetic, pharmaceutical and biomedical industries. Collagens play an important role in the structure and function of skin, cartilage, bone and connective tissue[1].

[Related Catalog]:

Research Areas >> Others

Signaling Pathways >> Others >> Others

[References]

[1]. Sorushanova A, et al. The Collagen Suprafamily: From Biosynthesis to Advanced Biomaterial Development. Adv Mater. 2019 Jan;31(1):e1801651.

Chemical & Physical Properties

[ Density]:
1.4±0.1 g/cm3

[ Boiling Point ]:
558.2±60.0 °C at 760 mmHg

[ Molecular Formula ]:
C₁₃H₂₄N₄O₄

[ Molecular Weight ]:
300.354

[ Flash Point ]:
291.4±32.9 °C

[ Exact Mass ]:
300.179749

[ LogP ]:
-0.82

[ Appearance of Characters ]:
solution

[ Vapour Pressure ]:
0.0±3.4 mmHg at 25°C

[ Index of Refraction ]:
1.604

[ Storage condition ]:
2-8°C

[ Water Solubility ]:
H2O: 5 mg/mL, hazy, colorless and viscous | It is soluble in water.

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
B

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
1

Articles

DOCK8 regulates lymphocyte shape integrity for skin antiviral immunity.

J. Exp. Med. 211(13) , 2549-66, (2014)

DOCK8 mutations result in an inherited combined immunodeficiency characterized by increased susceptibility to skin and other infections. We show that when DOCK8-deficient T and NK cells migrate throug...

Tissue-specific splice variants of HARE/Stabilin-2 are expressed in bone marrow, lymph node, and spleen.

Biochem. Biophys. Res. Commun. 456(1) , 257-61, (2015)

The hyaluronan receptor for endocytosis (HARE), or Stabilin-2, is the mammalian endocytic clearance receptor for HA, heparin, advanced glycation end-products, acetylated and oxidized low-density lipop...

Gelatin hydrogel as a carrier of recombinant human fibroblast growth factor-2 during rat mandibular distraction.

J. Oral Maxillofac. Surg. 72(10) , 2015-31, (2014)

The aim of the present study was to evaluate the feasibility of a gelatin hydrogel system to enhance recombinant human fibroblast growth factor-2 (rhFGF-2)-induced osteogenic effects during rat mandib...