Leupeptin hemisulfate salt

Names

[ Name ]:
Leupeptin hemisulfate salt

[Synonym ]:
L-Leucinamide, N-acetyl-L-leucyl-N-[(1S)-4-[(diaminomethylene)amino]-1-formylbutyl]-
AC-LLR-CHO
MFCD00037012
LEUPEPTIN SULFATE
N-acetyl-L-leucyl-N-[(1S)-4-{[amino(imino)methyl]amino}-1-formylbutyl]-L-leucinamide
AC-LEU-LEU-ARG-CHO
N-acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylidene)amino]-1-oxopentan-2-yl}-L-leucinamide
LEUPEPTIN 1/2 H2SO4
Leupeptin,synthetic
Leupeptin,Microbial
Leupeptin
N-Acetyl-L-leucyl-N-{(2S)-5-[(diaminomethylene)amino]-1-oxo-2-pentanyl}-L-leucinamide
AC-LEU-LEU-ARGININAL
N-Acetyl-L-leucyl-L-leucyl-L-argininal
Synonym Acetyl-Leu-L
Leupeptin (hemisulfate)

Biological Activity

[Description]:

Leupeptin hemisulfate is a reversible, competitive serine/cysteine protease inhibitor.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin

Research Areas >> Inflammation/Immunology

Peptides

[Related Small Molecules]

E-64 | PMSF | CA-074 methyl ester | LY 3000328 | Odanacatib(MK-0822) | CA 074 TFA | VBY-825 | Balicatib | Cysteine Protease inhibitor | Papain | MK-0822 | Cathepsin Inhibitor 2 | E-64c | MIV-247

Chemical & Physical Properties

[ Density]:
1.2±0.1 g/cm3

[ Molecular Formula ]:
C₂₀H₃₈N₆O_4.1/₂H₂SO₄

[ Molecular Weight ]:
475.59

[ PSA ]:
166.27000

[ LogP ]:
1.16

[ Index of Refraction ]:
1.557

[ Storage condition ]:
-20°C

MSDS

Click to get detail MSDS

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
22-24/25-36/37-36

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
29241900

Customs

[ HS Code ]: 29241900

Articles

IL-10 plays a pivotal role in anti-inflammatory effects of resveratrol in activated microglia cells.

Int. Immunopharmacol. 24(2) , 369-76, (2015)

The development of agents that can modulate microglial activation has been suggested as one potential strategy for the treatment or prevention of neurodegenerative diseases. Among these agents, resver...

Nerve growth factor-induced synapse-like structures in contralateral sensory ganglia contribute to chronic mirror-image pain.

Pain 156 , 2295-309, (2015)

Elevated nerve growth factor (NGF) in the contralateral dorsal root ganglion (DRG) mediates mirror-image pain after peripheral nerve injury, but the underlying mechanism remains unclear. Using intrath...

Calcium Regulates the Activity and Structural Stability of Tpr, a Bacterial Calpain-like Peptidase.

J. Biol. Chem. 290 , 27248-60, (2015)

Porphyromonas gingivalis is a peptide-fermenting asaccharolytic periodontal pathogen. Its genome contains several genes encoding cysteine peptidases other than gingipains. One of these genes (PG1055) ...