Cathepsin Inhibitor 2

Names

[ CAS No. ]:
1017931-53-1

[ Name ]:
Cathepsin Inhibitor 2

Biological Activity

[Description]:

Cathepsin Inhibitor 2 is a potent Cathepsin S inhibitor extracted from patent WO2009123623A1, has a Ki of <20 nM.

[Related Catalog]:

Signaling Pathways >> Metabolic Enzyme/Protease >> Cathepsin
Research Areas >> Cancer
Research Areas >> Inflammation/Immunology

[Target]

Ki: <20 nM (Cathepsin S)[1]


[In Vitro]

Cathepsin Inhibitor 2 (Please refer to paragraph 0229 for detailed information) potently inhibits Cathepsin S, Cathepsin F, Cathepsin L, and Cathepsin B with Kis of <20 nM, 21-500 nM, 21-500 nM, and 21-500 nM, respectively[1].

[References]

[1]. LINK, John, O, et al. DI-FLUORO CONTAINING COMPOUNDS AS CYSTEINE PROTEASE INHIBITORS. WO2009123623A1.


[Related Small Molecules]

Leupeptin hemisulfate salt | E-64 | PMSF | CA-074 methyl ester | LY 3000328 | Odanacatib(MK-0822) | CA 074 TFA | VBY-825 | Balicatib | Cysteine Protease inhibitor | Papain | MK-0822 | E-64c | MIV-247

Chemical & Physical Properties

[ Molecular Formula ]:
C19H21F6N3O

[ Molecular Weight ]:
421.38

Related Compounds