Published date: 2024-07-17 15:06:28
CAS number: 900308-84-1
Name: SEC inhibitor KL-1
Price:
$1900.0/1g
$950.0/250mg
$550.0/100mg
Purity: 98.0%
Stocking period: 3 Day
Stock: 3
Product Webpage: https://www.dcchemicals.com/product_show-KL-1.html
Detail Product Information:
SEC inhibitor KL-1 is a peptidomimetic inhibitor of super elongation complex (SEC) and transcription elongation by Pol II, disrupts cyclin T1-AFF4 interaction (Ki=3.48 uM) within SEC; disrupts the interaction between the SEC scaffolding protein AFF4 and P-TEFb, resulting in impaired release of Pol II from promoter-proximal pause sites and a reduced average rate of processive transcription elongation; attenuates the heat-shock response from Drosophila to human, reduces protein levels of SEC components AFF1 and AFF4, but not CDK9 or CCNT1 in HEK293T cells; downregulates MYC and MYC-dependent transcriptional programs in mammalian cells and delays tumor progression in mouse xenograft models of MYC-driven cancer.
Name: DC Chemicals Limited Recommended
Chemsrc Level: Verified
Product #: 34963
Tel: 58447131
Address: Jinyu Rd100, pudong
Area: China(Mainland)
Contact: Tony Cao
Contact Phone #: 13564518121
Email: sales@dcchemicals.com
Website: http://www.dcchemicals.com
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Detail
introduction:
D&C Chemicals provides a wide range of research chemicals and biochemicals including novel life-science reagents, reference compounds, APIs and Natural compounds for laboratory and scientific use.
D&C Chem has established a global network of thousands of customers from many research centers and Reagent companies in the USA, Europe and Japan.
We are the the official vendor of more than 500 universities and institutes including: Harvard University,Yale University,NIH/NCI, City of Hope ORG, PARTNERS ORG,John Hopkins University,Universit tsklinikum,Oxford University,Newcastle University,UNC,UCSF and many other universities and institutes. Our bioactive compounds received good feedback from our customers.
Our credo is committed to the adoption of different products, reliable quality, competitive prices and quality service to create value for customers.
Name: Shanghai Nianxing Industrial Co., Ltd
Area: China
Price:
$1900.0/1g
$950.0/250mg
$550.0/100mg
Contact: Yang
Product Detail: SEC inhibitor KL-1
Name: ShangHai DC Chemicals Co.,Ltd
Area: China
Price:
$1900.0/1g
$950.0/250mg
$550.0/100mg
Contact: Tony Lai
Product Detail: SEC inhibitor KL-1
Name: DC Chemicals Limited
Area: China
Price:
$1900.0/1g
$950.0/250mg
$550.0/100mg
Contact: Tony Cao
Product Detail: SEC inhibitor KL-1
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