Astaxanthin

Names

[ CAS No. ]:
472-61-7

[ Name ]:
Astaxanthin

[Synonym ]:
all-trans-Astaxanthin
(3S,3'S)-3,3'-Dihydroxy-β,β-carotene-4,4'-dione
Natupink
(3S,3'S)-all-trans-Astaxanthin
EINECS 207-451-4
(3S,3'S)-Astaxanthin
Astaxanthin(3,3-Dihydroxy-Beta,Beta-Carotene-4,4-Dione)
BioAstin
BioAstin oleoresin
Lucantin Pink
AstaREAL
Carophyll Pink
Astaxanthin Discontinued
MFCD00672621
3,3'-Dihydroxy-β,β-carotene-4,4'-dione

Biological Activity

[Description]:

Astaxanthin, a red dietary carotenoid isolated from Haematococcus pluvialis, is an inhibitor of PPARγ and a potent antioxidant with antiproliferative, neuroprotective and anti-inflammatory activity[1]. Astaxanthin has potential in the treatment of various diseases, such as cancers and Parkinson’s disease, cardiovascular disease[2]. Due to its bright red colour, Astaxanthin could be used as a food colorant in animal feeds[3].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

Natural Products >> Terpenoids and Glycosides

Research Areas >> Cancer

[Target]

PPARγ

[References]

[1]. Yang Y, et al. Epigenetic CpG Methylation of the Promoter and Reactivation of the Expression of GSTP1 by Astaxanthin in Human Prostate LNCaP Cells. AAPS J. 2017 Mar;19(2):421-430.

[2]. Desheng Fu, et al. Effect of astaxanthin on retinal pigment epithelial cells in high glucose: an invitro study. Biomedical Research 2017; 28 (15): 6839-6843.

[3]. Rachel K Johnston, et al. Effects of astaxanthin on Brachionus manjavacas (Rotifera) population growth. Aquaculture Research. 2018;49:2278–2287.

[Related Small Molecules]

GW9662 | Retinoic acid | Elafibranor | GW501516 | Troglitazone | T0070907 | Pemafibrate | CDDO-Im | Wy-14643 | GW0742 | GW1929 | FH535 | Icariin | Daidzein | Fisetin

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
774.0±60.0 °C at 760 mmHg

[ Melting Point ]:
215-216ºC

[ Molecular Formula ]:
C₄₀H₅₂O₄

[ Molecular Weight ]:
596.839

[ Flash Point ]:
435.8±29.4 °C

[ Exact Mass ]:
596.386536

[ PSA ]:
74.60000

[ LogP ]:
8.16

[ Vapour Pressure ]:
0.0±6.0 mmHg at 25°C

[ Index of Refraction ]:
1.595

[ Storage condition ]:
−20°C

[ Water Solubility ]:
DMSO: soluble1mg/mL (warmed)

Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xn: Harmful;

[ Risk Phrases ]:
R20/21/22

[ Safety Phrases ]:
S24/25

[ RIDADR ]:
NONH for all modes of transport

[ WGK Germany ]:
3

[ HS Code ]:
3203001990

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Customs

[ HS Code ]: 3203001990

Articles

Effect of AST on age-associated changes of vocal folds in a rat model.

Laryngoscope 124(10) , E411-7, (2014)

Reactive oxygen species (ROS) are associated with aging. Astaxanthin (AST) is a strong antioxidant and has been reported to prevent various ROS-induced diseases. In the current study, we investigated ...

Effect of dietary formic acid and astaxanthin on the survival and growth of Pacific white shrimp (Litopenaeus vannamei) and their resistance to Vibrio parahaemolyticus.

Springerplus 4 , 440, (2015)

A 90-day feeding trial was conducted to evaluate the effects of formic acid (FA) and astaxanthin (AX) on growth, survival, immune parameters, and tolerance to Vibrio infection in Pacific white shrimp....

Morphological, molecular, and biochemical characterization of astaxanthin-producing green microalga Haematococcus sp. KORDI03 (Haematococcaceae, Chlorophyta) isolated from Korea.

J. Microbiol. Biotechnol. 25(2) , 238-46, (2015)

A unicellular red microalga was isolated from environmental freshwater in Korea, and its morphological, molecular, and biochemical properties were characterized. Morphological analysis revealed that t...

Related Compounds

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