Ethyl 2-hydroxyacetate
Names
[ CAS No. ]:
623-50-7
[ Name ]:
Ethyl 2-hydroxyacetate
[Synonym ]:
ethyl 2-hydroxyacetate
Ethyl glycolate
ethyl hydroxyacetate
Acetic acid, 2-hydroxy-, ethyl ester
EINECS 210-798-4
MFCD00021970
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
156.7±8.0 °C at 760 mmHg
[ Molecular Formula ]:
C4H8O3
[ Molecular Weight ]:
104.104
[ Flash Point ]:
61.7±0.0 °C
[ Exact Mass ]:
104.047340
[ PSA ]:
46.53000
[ LogP ]:
-0.54
[ Vapour Pressure ]:
1.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.414
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- MC5410000
- CHEMICAL NAME :
- Glycolic acid, ethyl ester
- CAS REGISTRY NUMBER :
- 623-50-7
- BEILSTEIN REFERENCE NO. :
- 1743766
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 3
- MOLECULAR FORMULA :
- C4-H8-O3
- MOLECULAR WEIGHT :
- 104.12
- WISWESSER LINE NOTATION :
- Q1VO2
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - guinea pig
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 11,150,1959 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1500 mg/kg
- TOXIC EFFECTS :
- Behavioral - general anesthetic Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis
- REFERENCE :
- JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 11,150,1959
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36/37/39-S37/39
[ RIDADR ]:
1993
[ WGK Germany ]:
3
[ RTECS ]:
MC5410000
[ Packaging Group ]:
III
[ Hazard Class ]:
3.2
[ HS Code ]:
2918199090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918199090
[ Summary ]:
2918199090 other carboxylic acids with alcohol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:6.5%。General tariff:30.0%
Articles
Aldrichimica Acta 23 , 51, (1990)
Synthesis of ferrocenyl-substituted heterocycles: the beneficial effect of the microwave irradiation. Puciová M, et al.
Collect. Czech. Chem. Commun. 59(1) , 175-85, (1994)
Polycondensation of a-hydroxy acids by enzymes or PEG-modified enzymes in organic media. Ohya Y, et al.
J. Macromol. Sci., Part A: Pure Appl. Chem. 32(2) , 179-90, (1995)