Angiotensin I/II (4-8)

Names

[ CAS No. ]:
52530-60-6

[ Name ]:
Angiotensin I/II (4-8)

[Synonym ]:
De-(1-asp-2-arg-3-val)-angiotensin II
Angiotensin pentapeptide
Des-(asp(1)-arg(2)-val(3))-angiotensin II
L-tyrosyl-L-isoleucyl-L-histidyl-L-prolyl-L-phenylalanine
tyrosylisoleusylhidstudylprolylphenylalanine
angiotensin II (4-8)
Angiotensin II (4-8) pentapeptide
angiotensin (4-8)
Ang(4-8)
Tyrosinyl-isoleucinyl-histidinyl-prolinyl-phenylalanine
Tyr-Ile-His-Pro-Phe
(Des-1,2,3)angiotensin II

Biological Activity

[Description]:

Angiotensin I/II (4-8), a major metabolite of Angiotensin II, is a C-terminal 4-8 pentapeptide[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease

[References]

[1]. P F Semple, et al. Angiotensin II and its heptapeptide (2-8), hexapeptide (3-8), and pentapeptide (4-8) metabolites in arterial and venous blood of man. Circ Res. 1976 Nov;39(5):671-8.  

Chemical & Physical Properties

[ Density]:
1.316 g/cm3

[ Boiling Point ]:
1107.2ºC at 760 mmHg

[ Molecular Formula ]:
C35H45N7O7

[ Molecular Weight ]:
675.77400

[ Flash Point ]:
623.4ºC

[ Exact Mass ]:
675.33800

[ PSA ]:
219.84000

[ LogP ]:
2.85750

[ Index of Refraction ]:
1.617

Synthetic Route

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Precursor & DownStream

Precursor

DownStream

Related Compounds