m-C-tri(CH2-PEG1-NHSester)

Names

[ CAS No. ]:
173414-89-6

[ Name ]:
m-C-tri(CH2-PEG1-NHSester)

Biological Activity

[Description]:

m-C-tri(CH2-PEG1-NHS ester) is a non-cleavable 1 unit PEG ADC linker used in the synthesis of antibody-drug conjugates (ADCs)[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Non-cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker[1].

[References]

[1]. Beck A, et al. Strategies and challenges for the next generation of antibody-drug conjugates. Nat Rev Drug Discov. 2017 May;16(5):315-337.

Chemical & Physical Properties

[ Molecular Formula ]:
C26H33N3O15

[ Molecular Weight ]:
627.55

[ Storage condition ]:
-20°C

Related Compounds