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Mal-PEG1-NHS ester

Names

[ CAS No. ]:
1807518-72-4

[ Name ]:
Mal-PEG1-NHS ester

[Synonym ]:
1-(2-{3-[(2,5-Dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy}ethyl)-1H-pyrrole-2,5-dione
MFCD26127783
1H-Pyrrole-2,5-dione, 1-[2-[3-[(2,5-dioxo-1-pyrrolidinyl)oxy]-3-oxopropoxy]ethyl]-

Biological Activity

[Description]:

Mal-PEG1-NHS ester is a cleavable and PEG-based ADC linker used in the synthesis of antibody-drug conjugates (ADCs).

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> Antibody-drug Conjugate >> ADC Linker

[Target]

Cleavable


[In Vitro]

ADCs are comprised of an antibody to which is attached an ADC cytotoxin through an ADC linker.

Chemical & Physical Properties

[ Density]:
1.5±0.1 g/cm3

[ Boiling Point ]:
488.4±55.0 °C at 760 mmHg

[ Molecular Formula ]:
C13H14N2O7

[ Molecular Weight ]:
310.259

[ Flash Point ]:
249.2±31.5 °C

[ Exact Mass ]:
310.080109

[ LogP ]:
-1.89

[ Vapour Pressure ]:
0.0±1.2 mmHg at 25°C

[ Index of Refraction ]:
1.582

[ Storage condition ]:
-20°C

Related Compounds