Amino-PEG4-benzyl ester

Names

[ CAS No. ]:
1351397-21-1

[ Name ]:
Amino-PEG4-benzyl ester

Biological Activity

[Description]:

Amino-PEG4-benzyl ester is a PEG- and Alkyl/ether-based PROTAC linker that can be used in the synthesis of PROTACs[1].

[Related Catalog]:

Research Areas >> Cancer
Signaling Pathways >> PROTAC >> PROTAC Linker

[Target]

PEGs

Alkyl/ether


[In Vitro]

PROTACs contain two different ligands connected by a linker; one is a ligand for an E3 ubiquitin ligase and the other is for the target protein. PROTACs exploit the intracellular ubiquitin-proteasome system to selectively degrade target proteins[1].

[References]

[1]. Byung Chul Lee,et al. Synthesis and biological evaluation of RGD peptides with the 99mTc/188Re chelated iminodiacetate core: highly enhanced uptake and excretion kinetics of theranostics against tumor angiogenesis. RSC Advances, 2013, 3, 782.

Chemical & Physical Properties

[ Molecular Formula ]:
C18H29NO6

[ Molecular Weight ]:
355.43

Related Compounds