metaphit methanesulfonate
Names
[ CAS No. ]:
99287-12-4
[ Name ]:
metaphit methanesulfonate
Chemical & Physical Properties
[ Boiling Point ]:
433.7ºC at 760 mmHg
[ Molecular Formula ]:
C19H28N2O3S2
[ Molecular Weight ]:
396.56700
[ Flash Point ]:
216.1ºC
[ Exact Mass ]:
396.15400
[ PSA ]:
110.44000
[ LogP ]:
5.58890
[ Appearance of Characters ]:
solid | white
[ Storage condition ]:
−20°C
[ Stability ]:
Hygroscopic
[ Water Solubility ]:
H2O: soluble
MSDS
Safety Information
[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
Articles
Eur. J. Pharmacol. 161 , 273-277, (1989)
Pretreatment of guinea pig brain membranes with 1-[1-(3-isothiocyanatophenyl)cyclohexyl]piperidine (Metaphit) caused irreversible and differential inhibition of ligand binding to sigma (sigma) recepto...
Metaphit, a proposed phencyclidine (PCP) antagonist, prevents PCP-induced locomotor behavior through mechanisms unrelated to specific blockade of PCP receptors.Eur. J. Pharmacol. 140 , 267, (1987)
Metaphit, a derivative of phencyclidine (PCP) which irreversibly binds to a population of PCP receptor sites in rat brain, has been considered as a potentially specific PCP antagonist. In whole animal...
Long-term blockade of the dopamine uptake complex by metaphit, an isothiocyanate derivative of phencyclidine.Synapse 3 , 239-245, (1989)
[3H]Mazindol was used to label the dopamine uptake complex in mouse striatum in vitro in the presence and absence of metaphit, an isothiocyanate derivative of phencyclidine. In some experiments, metap...