3-Hydroxybenzoicacid
Names
[ CAS No. ]:
99-06-9
[ Name ]:
3-Hydroxybenzoicacid
[Synonym ]:
3-Hydroxybenzoic acid
m-salicylicacid
3-hydroxy-benzoicaci
m-hydroxy-benzoicaci
MFCD00002506
Benzoic acid, 3-hydroxy-
RARECHEM AL BO 0049
m-Hba
3-Carboxyphenol
m-hydroxylbenzoic acid
3-Hydroxy benzoic acid
m-Oxybenzoic acid
META-HYDROXYBENZOIC ACID
EINECS 202-726-5
m-Hydroxybenzoic
3-Hydroxybenzoicacid
3-hydroxybenzoate
Chemical & Physical Properties
[ Density]:
1.4±0.1 g/cm3
[ Boiling Point ]:
346.1±25.0 °C at 760 mmHg
[ Melting Point ]:
201 °C
[ Molecular Formula ]:
C7H6O3
[ Molecular Weight ]:
138.121
[ Flash Point ]:
177.3±19.7 °C
[ Exact Mass ]:
138.031693
[ PSA ]:
57.53000
[ LogP ]:
1.50
[ Vapour Pressure ]:
0.0±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.616
[ Water Solubility ]:
slightly soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DH1924980
- CHEMICAL NAME :
- Benzoic acid, m-hydroxy-
- CAS REGISTRY NUMBER :
- 99-06-9
- BEILSTEIN REFERENCE NO. :
- 0508160
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 4
- MOLECULAR FORMULA :
- C7-H6-O3
- MOLECULAR WEIGHT :
- 138.13
- WISWESSER LINE NOTATION :
- QVR CQ
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 3700 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- BCFAAI Bollettino Chimico Farmaceutico. (Societa Editoriale Farmaceutica, Via Ausonio 12, 20123 Milan, Italy) V.33- 1894- Volume(issue)/page/year: 112,53,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- QJPPAL Quarterly Journal of Pharmacy & Pharmacology. (London, UK) V.2-21, 1929-48. For publisher information, see JPPMAB. Volume(issue)/page/year: 19,483,1946 ** REPRODUCTIVE DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Subcutaneous
- DOSE :
- 400 mg/kg
- SEX/DURATION :
- female 11 day(s) after conception
- TOXIC EFFECTS :
- Reproductive - Effects on Embryo or Fetus - fetal death
- REFERENCE :
- RCOCB8 Research Communications in Chemical Pathology and Pharmacology. (PJD Pub. Ltd., P.O. Box 966, Westbury, NY 11590) V.1- 1970- Volume(issue)/page/year: 38,209,1982
Safety Information
[ Symbol ]:
GHS07
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302-H315-H319-H335
[ Precautionary Statements ]:
P261-P305 + P351 + P338
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant;
[ Risk Phrases ]:
R36/37/38
[ Safety Phrases ]:
S26-S36-S37/39
[ RIDADR ]:
NONH for all modes of transport
[ WGK Germany ]:
3
[ RTECS ]:
DH1924980
[ HS Code ]:
2918290000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2918290000
[ Summary ]:
HS: 2918290000 other carboxylic acids with phenol function but without other oxygen function, their anhydrides, halides, peroxides, peroxyacids and their derivatives Tax rebate rate:9.0% Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward) VAT:17.0% MFN tariff:6.5% General tariff:30.0%
Articles
Environ. Sci. Pollut. Res. Int. 21(14) , 8406-16, (2014)
The electrochemical degradation of the nonsteroidal anti-inflammatory drug ketoprofen in tap water has been studied using electro-Fenton (EF) and anodic oxidation (AO) processes with platinium (Pt) an...
Antagonistic control of a dual-input mammalian gene switch by food additives.Nucleic Acids Res. 42(14) , e116, (2014)
Synthetic biology has significantly advanced the design of mammalian trigger-inducible transgene-control devices that are able to programme complex cellular behaviour. Fruit-based benzoate derivatives...
DNA-Linked Enzyme-Coupled Assay for Probing Glucosyltransferase Specificity.ACS Synth. Biol. 4 , 833-41, (2015)
Traditional enzyme characterization methods are low-throughput and therefore limit engineering efforts in synthetic biology and biotechnology. Here, we propose a DNA-linked enzyme-coupled assay (DLEnC...