DMT-dA(bz) Phosphoramidite

Names

[ Name ]:
DMT-dA(bz) Phosphoramidite

[Synonym ]:
Adenosine, N-benzoyl-5'-O-[bis(4-methoxyphenyl)phenylmethyl]-3'-O-[[bis(1-methylethyl)amino](2-cyanoethoxy)phosphino]-2'-deoxy-
5'-O-(4,4'-Dimethoxytrityl)-N6-benzoyl-2'-deoxyadenosine-3'-(2-cyanoethyl-N,N-diisopropyl)phosphoramidite
(2R,3S,5R)-5-(6-benzamido-9H-purin-9-yl)-2-((bis(4-methoxyphenyl)(phenyl)methoxy)methyl)tetrahydrofuran-3-yl (2-cyanoethyl) diisopropylphosphoramidite
N-Benzoyl-5'-O-[bis(4-methoxyphenyl)(phenyl)methyl]-3'-O-[(2-cyanoethoxy)(diisopropylamino)phosphino]-2'-deoxyadenosine
DMT-dA(Bz)-CE-Phosphoramidite

Biological Activity

[Description]:

DMT-dA(bz) Phosphoramidite is typically used in the synthesis of DNA[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> DNA/RNA Synthesis

Research Areas >> Others

[References]

[1]. James D Thorpe, et al. Mechanochemical Synthesis of Short DNA Fragments. Chemistry. 2020 Jul 22;26(41):8857-8861.

Chemical & Physical Properties

[ Molecular Formula ]:
C₄₇H₅₂N₇O₇P

[ Molecular Weight ]:
857.932

[ Exact Mass ]:
857.366577

[ PSA ]:
168.70000

[ LogP ]:
9.95

[ Appearance of Characters ]:
white to off-white

[ Storage condition ]:
Store at -20°C

[ Water Solubility ]:
soluble, clear

MSDS

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Safety Information

[ Personal Protective Equipment ]:
Eyeshields;Gloves;type N95 (US);type P1 (EN143) respirator filter

[ Hazard Codes ]:
Xi

[ RIDADR ]:
NONH for all modes of transport

[ HS Code ]:
2903890090

Synthetic Route

Click to get detail synthetic route

Customs

[ HS Code ]: 2903890090

[ Summary ]:
2903890090. halogenated derivatives of cyclanic, cyclenic or cyclotherpenic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%