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Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

Names

[ CAS No. ]:
98092-14-9

[ Name ]:
Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH

[Synonym ]:
Isovaleryl-Phe-Nle-Sta-Ala-Sta-OH
Pepstatin A, 1-[N-(3-methyl-1-oxobutyl)-L-phenylalanine]-2-L-norleucine-
L-Norleucinamide, N-(3-methyl-1-oxobutyl)-L-phenylalanyl-N-[4-[[2-[[1-(2-carboxy-1-hydroxyethyl)-3-methylbutyl]amino]-1-methyl-2-oxoethyl]amino]-2-hydroxy-1-(2-methylpropyl)-4-oxobutyl]-, [1S-[1R*,2R*,4[R*[R*(R*)]]]]-

Biological Activity

[Description]:

SR 42128 is a potent renin inhibitor. SR 42128 potently inhibits primate renins whereas other animal renins are much less inhibited[1].

[Related Catalog]:

Research Areas >> Cardiovascular Disease
Signaling Pathways >> Metabolic Enzyme/Protease >> Renin

[References]

[1]. M De Claviere, et al. In vitro and in vivo inhibition of human and primate renin by a new potent renin inhibitor: SR 42128. J Cardiovasc Pharmacol. 1985:7 Suppl 4:S58-61.  

Chemical & Physical Properties

[ Density]:
1.138±0.06 g/cm3 (20 °C, 760 mmHg)

[ Boiling Point ]:
1064.9±65.0 °C (760 mmHg)

[ Molecular Formula ]:
C39H65N5O9

[ Molecular Weight ]:
747.96100

[ Exact Mass ]:
747.47800

[ PSA ]:
223.26000

[ LogP ]:
4.54260

Related Compounds