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Ethyl lactate

Names

[ CAS No. ]:
97-64-3

[ Name ]:
Ethyl lactate

[Synonym ]:
(±)-Ethyl 2-hydroxypropionate
QY1&VO2
(±)-Ethyl lactate
Actylol
(±)-Ethyl 2-hydroxypropanoate
Purasolv ELS
FEMA 2440
2-Hydroxypropanoic acid ethyl ester
Ethyl 2-hydroxypropanoate
lactic acid ethyl ester
Acytol
Ethyl α-hydroxypropionate
yl lactate
ethyl 2-hydroxypropionate
Eusolvan
Solactol
MFCD00065359
Ethyl lactate
Ethyl ester of lactic acid
EthyI lactate
Ethyllactat
Propanoic acid, 2-hydroxy-, ethyl ester
dl-ethyl lactate
EINECS 202-598-0

Chemical & Physical Properties

[ Density]:
1.1±0.1 g/cm3

[ Boiling Point ]:
154.5±0.0 °C at 760 mmHg

[ Melting Point ]:
-26°C

[ Molecular Formula ]:
C5H10O3

[ Molecular Weight ]:
118.131

[ Flash Point ]:
48.9±0.0 °C

[ Exact Mass ]:
118.062996

[ PSA ]:
46.53000

[ LogP ]:
-0.19

[ Vapour Pressure ]:
1.2±0.6 mmHg at 25°C

[ Index of Refraction ]:
1.420

[ Stability ]:
Stable. Combustible. Incompatible with strong oxidizing agents.

MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :
OD5075000
CHEMICAL NAME :
Lactic acid, ethyl ester
CAS REGISTRY NUMBER :
97-64-3
BEILSTEIN REFERENCE NO. :
1209448
LAST UPDATED :
199701
DATA ITEMS CITED :
10
MOLECULAR FORMULA :
C5-H10-O3
MOLECULAR WEIGHT :
118.15
WISWESSER LINE NOTATION :
QVY1&O2

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,677,1982
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intraperitoneal
SPECIES OBSERVED :
Rodent - rat
DOSE/DURATION :
1 gm/kg
TOXIC EFFECTS :
Behavioral - muscle weakness Lungs, Thorax, or Respiration - cyanosis Lungs, Thorax, or Respiration - other changes
REFERENCE :
JPPMAB Journal of Pharmacy and Pharmacology. (Pharmaceutical Soc. of Great Britain, 1 Lambeth High St., London SEI 7JN, UK) V.1- 1949- Volume(issue)/page/year: 11,150,1959
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Oral
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,89,1939
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Subcutaneous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
2500 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,89,1939
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Intravenous
SPECIES OBSERVED :
Rodent - mouse
DOSE/DURATION :
600 mg/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 65,89,1939
TYPE OF TEST :
LD50 - Lethal dose, 50 percent kill
ROUTE OF EXPOSURE :
Administration onto the skin
SPECIES OBSERVED :
Rodent - rabbit
DOSE/DURATION :
>5 gm/kg
TOXIC EFFECTS :
Details of toxic effects not reported other than lethal dose value
REFERENCE :
FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 20,677,1982
TYPE OF TEST :
LDLo - Lowest published lethal dose
ROUTE OF EXPOSURE :
Intramuscular
SPECIES OBSERVED :
Rodent - guinea pig
DOSE/DURATION :
2605 mg/kg
TOXIC EFFECTS :
Lungs, Thorax, or Respiration - dyspnea
REFERENCE :
JPETAB Journal of Pharmacology and Experimental Therapeutics. (Williams & Wilkins Co., 428 E. Preston St., Baltimore, MD 21202) V.1- 1909/10- Volume(issue)/page/year: 76,189,1942 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - A1136 No. of Facilities: 41 (estimated) No. of Industries: 2 No. of Occupations: 8 No. of Employees: 578 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - A1136 No. of Facilities: 298 (estimated) No. of Industries: 5 No. of Occupations: 23 No. of Employees: 7298 (estimated) No. of Female Employees: 1962 (estimated)

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS07

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H226-H318-H335

[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338

[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
Xi:Irritant

[ Risk Phrases ]:
R10;R37;R41

[ Safety Phrases ]:
S24-S26-S39

[ RIDADR ]:
1192

[ RTECS ]:
OD5075000

[ Packaging Group ]:
III

[ Hazard Class ]:
3.2

[ HS Code ]:
2918110000

Synthetic Route

Precursor & DownStream

Customs

[ HS Code ]: 2918110000

[ Summary ]:
2918110000. lactic acid, its salts and esters. VAT:17.0%. Tax rebate rate:13.0%. Supervision conditions:AB(certificate of inspection for goods inward,certificate of inspection for goods outward). MFN tariff:6.5%. General tariff:30.0%

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