1,3-Dibromo-2-propanol
Names
[ CAS No. ]:
96-21-9
[ Name ]:
1,3-Dibromo-2-propanol
[Synonym ]:
EINECS 202-489-8
MFCD00000216
1,3-dibromopropan-2-ol
1,3-Dibromo-2-propanol
2-Propanol, 1,3-dibromo-
Chemical & Physical Properties
[ Density]:
2.1±0.1 g/cm3
[ Boiling Point ]:
194.3±0.0 °C at 760 mmHg
[ Molecular Formula ]:
C3H6Br2O
[ Molecular Weight ]:
217.887
[ Flash Point ]:
46.7±0.0 °C
[ Exact Mass ]:
215.878525
[ PSA ]:
20.23000
[ LogP ]:
1.48
[ Vapour Pressure ]:
0.1±0.8 mmHg at 25°C
[ Index of Refraction ]:
1.556
[ Storage condition ]:
Refrigerator
[ Water Solubility ]:
soluble
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UB0200000
- CHEMICAL NAME :
- 2-Propanol, 1,3-dibromo-
- CAS REGISTRY NUMBER :
- 96-21-9
- BEILSTEIN REFERENCE NO. :
- 1732074
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 5
- MOLECULAR FORMULA :
- C3-H6-Br2-O
- MOLECULAR WEIGHT :
- 217.91
- WISWESSER LINE NOTATION :
- E1YQ1E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 150 mg/kg
- TOXIC EFFECTS :
- Tumorigenic - protects against induction of experimental tumors
MUTATION DATA
- TYPE OF TEST :
- DNA inhibition
- TEST SYSTEM :
- Human HeLa cell
- DOSE/DURATION :
- 1600 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 92,427,1982
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H301-H315-H319-H335-H351
[ Precautionary Statements ]:
P261-P281-P301 + P310-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic;Xn:Harmful;
[ Risk Phrases ]:
R10;R24/25;R36/37/38;R68
[ Safety Phrases ]:
S16-S26-S36/37/39-S45
[ RIDADR ]:
UN 1987 3/PG 3
[ WGK Germany ]:
3
[ RTECS ]:
UB0200000
[ Packaging Group ]:
II
[ Hazard Class ]:
3.2
[ HS Code ]:
2905590090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2905590090
[ Summary ]:
2905590090 other halogenated, sulphonated, nitrated or nitrosated derivatives of acyclic alcohols。Supervision conditions:None。VAT:17.0%。Tax rebate rate:9.0%。MFN tariff:5.5%。General tariff:30.0%
Articles
J. Med. Chem. 47(1) , 254-61, (2004)
A novel group of hybrid calcium channel (CC) modulators was prepared where the isopropyl ester moiety of isopropyl 1,4-dihydro-2,6-dimethyl-3-nitro-4-(2,1,3-benzoxadiazol-4-yl)pyridine-5-carboxylate (...
Sugar-pendant diamines.J. Org. Chem. 66(11) , 3783-9, (2001)
A set of 1,3-propanediamine derivatives connected to carbohydrates (5) has been prepared in four steps from peracetylated sugar and 1,3-dibromo-2-propanol in 60-73% yields. D-Glucose, D-mannose, D-gal...
Palladium-phosphorus/sulfur nanoparticles (NPs) decorated on graphene oxide: synthesis using the same precursor for NPs and catalytic applications in Suzuki-Miyaura coupling.Nanoscale 6(9) , 4588-97, (2014)
PdP2 and Pd4S nanoparticles (NPs) (size: ∼2-6 and 9-15 nm respectively) have been prepared for the first time from a single source precursor complex [Pd(L)Cl2] (1) by its one pot thermolysis at 200 °C...