Epibromohydrin
Names
[ CAS No. ]:
3132-64-7
[ Name ]:
Epibromohydrin
[Synonym ]:
1-Bromo-2,3-epoxypropane
EINECS 221-525-3
2-Bromomethyl
2-bromomethyloxiran
Epibromohydrine
2-(Bromomethyl)oxirane
epibromhidrina
Oxirane, 2-(bromomethyl)-
Epibromohydrin
1,2-epoxy-3-bromopropane
Glycidyl bromide
MFCD00005130
3-Bromopropylene Oxide
Epibromhydrin
UNII:8E89677I6B
Chemical & Physical Properties
[ Density]:
1.7±0.1 g/cm3
[ Boiling Point ]:
135.0±15.0 °C at 760 mmHg
[ Melting Point ]:
−40 °C(lit.)
[ Molecular Formula ]:
C3H5BrO
[ Molecular Weight ]:
136.975
[ Flash Point ]:
56.1±0.0 °C
[ Exact Mass ]:
135.952377
[ PSA ]:
12.53000
[ LogP ]:
0.85
[ Vapour Pressure ]:
9.7±0.2 mmHg at 25°C
[ Index of Refraction ]:
1.504
[ Stability ]:
Stable. Incompatible with acids, bases, oxidizing agents, many of the more active metals.
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TX4115000
- CHEMICAL NAME :
- Propane, 3-bromo-1,2-epoxy-
- CAS REGISTRY NUMBER :
- 3132-64-7
- BEILSTEIN REFERENCE NO. :
- 0079786
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 14
- MOLECULAR FORMULA :
- C3-H5-Br-O
- MOLECULAR WEIGHT :
- 136.99
- WISWESSER LINE NOTATION :
- T3OTJ B1E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 300 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
MUTATION DATA
- TYPE OF TEST :
- Sister chromatid exchange
- TEST SYSTEM :
- Rodent - hamster Lung
- DOSE/DURATION :
- 50 umol/L
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 249,55,1991 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - X6241 No. of Facilities: 7 (estimated) No. of Industries: 1 No. of Occupations: 1 No. of Employees: 1822 (estimated) No. of Female Employees: 272 (estimated)
Safety Information
[ Symbol ]:
GHS02, GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H226-H302-H315-H319-H335-H351
[ Precautionary Statements ]:
P261-P281-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn
[ Risk Phrases ]:
R23/24/25;R34
[ Safety Phrases ]:
S26-S36/37
[ RIDADR ]:
UN 2558 6.1/PG 1
[ WGK Germany ]:
2
[ RTECS ]:
TX4115000
[ Packaging Group ]:
I
[ Hazard Class ]:
6.1(a)
[ HS Code ]:
2910900090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2910900090
[ Summary ]:
2910900090. epoxides, epoxyalcohols, epoxyphenols and epoxyethers, with a three-membered ring, and their halogenated, sulphonated, nitrated or nitrosated derivatives. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Angew. Chem. Int. Ed. Engl. 54 , 9881-5, (2015)
Opportunistic pathogens exploit diverse strategies to sabotage host defenses. Pseudomonas aeruginosa secretes the CFTR inhibitory factor Cif and thus triggers loss of CFTR, an ion channel required for...