Benzophenone
Names
[ CAS No. ]:
119-61-9
[ Name ]:
Benzophenone
[Synonym ]:
Diphenylmethanone
Kayacure BP
Benzophenone
RVR
MFCD00003076
Diphenylketone
α-Oxoditane
Methanone, diphenyl-
α-Oxodiphenylmethane
A-Oxodiphenylmethane
EINECS 204-337-6
A-Oxoditane
Speedcure BP
Adjutan 6016
Mettler-Toledo Calibration substance ME 18870,Benzophenone
diphenyl ketone
Ketone, diphenyl
Benzoylbenzene
UNII-701M4TTV9O
Biological Activity
[Description]:
[Related Catalog]:
[Target]
Human Endogenous Metabolite
Chemical & Physical Properties
[ Density]:
1.1±0.1 g/cm3
[ Boiling Point ]:
305.4±0.0 °C at 760 mmHg
[ Melting Point ]:
47-51 °C(lit.)
[ Molecular Formula ]:
C13H10O
[ Molecular Weight ]:
182.218
[ Flash Point ]:
123.7±13.7 °C
[ Exact Mass ]:
182.073166
[ PSA ]:
17.07000
[ LogP ]:
3.18
[ Vapour density ]:
4.21 (vs air)
[ Vapour Pressure ]:
0.0±0.6 mmHg at 25°C
[ Index of Refraction ]:
1.584
[ Stability ]:
Stable. Incompatible with strong oxidizing agents, strong reducing agents. Combustible.
[ Water Solubility ]:
insoluble (
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- DI9950000
- CHEMICAL NAME :
- Benzophenone
- CAS REGISTRY NUMBER :
- 119-61-9
- LAST UPDATED :
- 199712
- DATA ITEMS CITED :
- 15
- MOLECULAR FORMULA :
- C13-H10-O
- MOLECULAR WEIGHT :
- 182.23
- WISWESSER LINE NOTATION :
- RVR
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- >10 gm/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,873,1973
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 2895 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9. Volume(issue)/page/year: 9,99,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Intraperitoneal
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 727 mg/kg
- TOXIC EFFECTS :
- Behavioral - somnolence (general depressed activity) Behavioral - tremor Lungs, Thorax, or Respiration - other changes
- REFERENCE :
- EJTXAZ European Journal of Toxicology and Environmental Hygiene. (Paris, France) V.7-9, 1974-76. For publisher information, see TOERD9. Volume(issue)/page/year: 9,99,1976
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 3535 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- FCTXAV Food and Cosmetics Toxicology. (London, UK) V.1-19, 1963-81. For publisher information, see FCTOD7. Volume(issue)/page/year: 11,873,1973 ** OTHER MULTIPLE DOSE TOXICITY DATA **
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 14 gm/kg/28D-C
- TOXIC EFFECTS :
- Blood - pigmented or nucleated red blood cells Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Blood - changes in erythrocyte (RBC) count
- REFERENCE :
- FCTOD7 Food and Chemical Toxicology. (Pergamon Press Inc., Maxwell House, Fairview Park, Elmsford, NY 10523) V.20- 1982- Volume(issue)/page/year: 29,741,1971
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 91 gm/kg/13W-C
- TOXIC EFFECTS :
- Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 14,221,1994
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 109 gm/kg/13W-C
- TOXIC EFFECTS :
- Liver - changes in liver weight Blood - changes in serum composition (e.g. TP, bilirubin, cholesterol) Nutritional and Gross Metabolic - weight loss or decreased weight gain
- REFERENCE :
- TOXID9 Toxicologist. (Soc. of Toxicology, Inc., 475 Wolf Ledge Parkway, Akron, OH 44311) V.1- 1981- Volume(issue)/page/year: 14,221,1994
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - guinea pig
- DOSE/DURATION :
- 75 mg/kg/15D-I
- TOXIC EFFECTS :
- Liver - other changes Liver - hepatitis, fibrous (cirrhosis, post-necrotic scarring)
- REFERENCE :
- BECTA6 Bulletin of Environmental Contamination and Toxicology. (Springer-Verlag New York, Inc., Service Center, 44 Hartz Way, Secaucus, NJ 07094) V.1- 1966- Volume(issue)/page/year: 50,282,1993 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - 83170 No. of Facilities: 1495 (estimated) No. of Industries: 8 No. of Occupations: 11 No. of Employees: 6944 (estimated) NOES - National Occupational Exposure Survey (1983) NOES Hazard Code - 83170 No. of Facilities: 1809 (estimated) No. of Industries: 27 No. of Occupations: 50 No. of Employees: 41516 (estimated) No. of Female Employees: 18162 (estimated)
Safety Information
[ Symbol ]:
GHS08, GHS09
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H351-H410
[ Precautionary Statements ]:
P273-P281-P501
[ Personal Protective Equipment ]:
dust mask type N95 (US);Eyeshields;Gloves
[ Hazard Codes ]:
Xi:Irritant
[ Risk Phrases ]:
R36/37/38;R50/53
[ Safety Phrases ]:
S26-S61-S37/39-S29-S60-S36-S62-S36/37-S33-S16-S9
[ RIDADR ]:
UN 3077 9/PG 3
[ WGK Germany ]:
2
[ RTECS ]:
DI9950000
[ Packaging Group ]:
III
[ Hazard Class ]:
9
[ HS Code ]:
2914399090
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2914399090
[ Summary ]:
2914399090. other aromatic ketones without other oxygen function. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
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