TRIBROMOHYDRIN
Names
[ CAS No. ]:
96-11-7
[ Name ]:
TRIBROMOHYDRIN
[Synonym ]:
Glycerol tribromohydrin
1,2,3-tribrompropane
Propane,1,2,3-tribromo
1,2,3-Tribromopropane
sym-Tribromopropane
1,2,3-tribromo propane
MFCD00017884
Glyceryl tribromohydrin
TRIBROMOHYDRIN
Allyl Tribromide
EINECS 202-478-8
tribromo-1,2,3 propane
glyceroltribromhydrine
s-Tribromopropane
1,2,3-Tribrom-propan
Propane, 1,2,3-tribromo-
Chemical & Physical Properties
[ Density]:
2.4±0.1 g/cm3
[ Boiling Point ]:
220.5±8.0 °C at 760 mmHg
[ Melting Point ]:
16-17 °C(lit.)
[ Molecular Formula ]:
C3H5Br3
[ Molecular Weight ]:
280.784
[ Flash Point ]:
87.7±13.2 °C
[ Exact Mass ]:
277.794128
[ LogP ]:
3.31
[ Vapour Pressure ]:
0.2±0.4 mmHg at 25°C
[ Index of Refraction ]:
1.577
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- TZ8300000
- CHEMICAL NAME :
- Propane, 1,2,3-tribromo-
- CAS REGISTRY NUMBER :
- 96-11-7
- BEILSTEIN REFERENCE NO. :
- 1732082
- LAST UPDATED :
- 199701
- DATA ITEMS CITED :
- 12
- MOLECULAR FORMULA :
- C3-H5-Br3
- MOLECULAR WEIGHT :
- 280.81
- WISWESSER LINE NOTATION :
- E1YE1E
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- LDLo - Lowest published lethal dose
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 500 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Oral
- DOSE :
- 250 mg/kg
- SEX/DURATION :
- male 5 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Fertility - pre-implantation mortality (e.g. reduction in number of implants per female; total number of implants per corpora lutea) Reproductive - Fertility - post-implantation mortality (e.g. dead and/or resorbed implants per total number of implants) Reproductive - Fertility - litter size (e.g. # fetuses per litter; measured before birth)
- TYPE OF TEST :
- TDLo - Lowest published toxic dose
- ROUTE OF EXPOSURE :
- Intraperitoneal
- DOSE :
- 23869 ug/kg
- SEX/DURATION :
- male 1 day(s) pre-mating
- TOXIC EFFECTS :
- Reproductive - Paternal Effects - testes, epididymis, sperm duct Reproductive - Paternal Effects - other effects on male Reproductive - Specific Developmental Abnormalities - urogenital system
- TYPE OF TEST :
- DNA damage
MUTATION DATA
- TEST SYSTEM :
- Rodent - rat
- DOSE/DURATION :
- 250 mg/kg/5D (Continuous)
- REFERENCE :
- MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 101,321,1982 *** NIOSH STANDARDS DEVELOPMENT AND SURVEILLANCE DATA *** NIOSH OCCUPATIONAL EXPOSURE SURVEY DATA : NOHS - National Occupational Hazard Survey (1974) NOHS Hazard Code - M1864 No. of Facilities: 8 (estimated) No. of Industries: 1 No. of Occupations: 6 No. of Employees: 176 (estimated)
Safety Information
[ Symbol ]:
GHS07, GHS08
[ Signal Word ]:
Warning
[ Hazard Statements ]:
H302 + H312 + H332-H315-H319-H335-H351
[ Precautionary Statements ]:
P261-P280-P305 + P351 + P338
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
Xn:Harmful;
[ Risk Phrases ]:
R20/21/22;R36/37/38;R68
[ Safety Phrases ]:
S26-S27-S36/37/39
[ RIDADR ]:
2810
[ WGK Germany ]:
3
[ RTECS ]:
TZ8300000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1(b)
[ HS Code ]:
2903399090
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2903399090
[ Summary ]:
2903399090. brominated,fluorinated or iodinated derivatives of acyclic hydrocarbons. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:5.5%. General tariff:30.0%
Articles
Environ. Mol. Mutagen. 12(2) , 253-9, (1988)
1,2,3-Tribromopropane, 1,2,3-trichloropropane, and 1,2-dibromo-3-chloropropane are mutagenic in strains TA1535 and TA100 of Salmonella typhimurium, but only in the presence of rat liver S9 mix. This r...