Allyl methacrylate
Names
[ CAS No. ]:
96-05-9
[ Name ]:
Allyl methacrylate
[Synonym ]:
EINECS 202-473-0
MFCD00008592
prop-2-enyl 2-methylprop-2-enoate
Chemical & Physical Properties
[ Density]:
0.938 g/mL at 25 °C(lit.)
[ Boiling Point ]:
59-61 °C43 mm Hg(lit.)
[ Melting Point ]:
-65 °C
[ Molecular Formula ]:
C7H10O2
[ Molecular Weight ]:
126.15300
[ Flash Point ]:
33.9±0.0 °C
[ Exact Mass ]:
126.06800
[ PSA ]:
26.30000
[ LogP ]:
1.29170
[ Vapour Pressure ]:
4.6 mm Hg ( 20 °C)
[ Index of Refraction ]:
n20/D 1.436(lit.)
[ Water Solubility ]:
4 g/L (20 ºC)
MSDS
Toxicological Information
CHEMICAL IDENTIFICATION
- RTECS NUMBER :
- UD3483000
- CHEMICAL NAME :
- 2-Propenoic acid, 2-methyl-, 2-propenyl ester
- CAS REGISTRY NUMBER :
- 96-05-9
- BEILSTEIN REFERENCE NO. :
- 1747406
- LAST UPDATED :
- 199710
- DATA ITEMS CITED :
- 10
- MOLECULAR FORMULA :
- C7-H10-O2
- MOLECULAR WEIGHT :
- 126.17
- WISWESSER LINE NOTATION :
- 1UY1&VO2U1
HEALTH HAZARD DATA
ACUTE TOXICITY DATA
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,371,1986
- TYPE OF TEST :
- Standard Draize test
- ROUTE OF EXPOSURE :
- Administration into the eye
- SPECIES OBSERVED :
- Rodent - rabbit
- REFERENCE :
- 85JCAE "Prehled Prumyslove Toxikologie; Organicke Latky," Marhold, J., Prague, Czechoslovakia, Avicenum, 1986 Volume(issue)/page/year: -,371,1986 ** ACUTE TOXICITY DATA **
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 70 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 34(8),59,1990
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - rat
- DOSE/DURATION :
- 1800 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 34(8),59,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Oral
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 57 mg/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 34(8),59,1990
- TYPE OF TEST :
- LC50 - Lethal concentration, 50 percent kill
- ROUTE OF EXPOSURE :
- Inhalation
- SPECIES OBSERVED :
- Rodent - mouse
- DOSE/DURATION :
- 5500 mg/m3
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- GTPZAB Gigiena Truda i Professional'nye Zabolevaniya. Labor Hygiene and Occupational Diseases. (V/O Mezhdunarodnaya Kniga, 113095 Moscow, USSR) V.1-36, 1957-1992. For publisher information, see MTPEEI Volume(issue)/page/year: 34(8),59,1990
- TYPE OF TEST :
- LD50 - Lethal dose, 50 percent kill
- ROUTE OF EXPOSURE :
- Administration onto the skin
- SPECIES OBSERVED :
- Rodent - rabbit
- DOSE/DURATION :
- 500 uL/kg
- TOXIC EFFECTS :
- Details of toxic effects not reported other than lethal dose value
- REFERENCE :
- AIHAAP American Industrial Hygiene Association Journal. (AIHA, 475 Wolf Ledges Pkwy., Akron, OH 44311) V.19- 1958- Volume(issue)/page/year: 30,470,1969
Safety Information
[ Symbol ]:
GHS02, GHS06, GHS08, GHS09
[ Signal Word ]:
Danger
[ Hazard Statements ]:
H226-H302-H311-H330-H373-H410
[ Precautionary Statements ]:
P210-P260-P280-P302 + P352 + P312-P304 + P340 + P310-P370 + P378
[ Target Organs ]:
Liver
[ Personal Protective Equipment ]:
Eyeshields;Faceshields;full-face respirator (US);Gloves;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter
[ Hazard Codes ]:
T:Toxic
[ Risk Phrases ]:
R10;R21/22;R23;R50
[ Safety Phrases ]:
S36/37-S45-S61
[ RIDADR ]:
UN 2929 6.1/PG 2
[ WGK Germany ]:
2
[ RTECS ]:
UD3483000
[ Packaging Group ]:
II
[ Hazard Class ]:
6.1
[ HS Code ]:
2916140000
Synthetic Route
Precursor & DownStream
Precursor
DownStream
Customs
[ HS Code ]: 2916140000
[ Summary ]:
2916140000. other esters of methacrylic acid. VAT:17.0%. Tax rebate rate:13.0%. . MFN tariff:6.5%. General tariff:80.0%
Articles
Dent. Mater. J. 28(6) , 722-9, (2009)
It has been established that the toxicity of acrylate and methacrylate monomers is driven by their reactivity towards glutathione (GSH). With this relationship, the objective of this study was to pred...
Glutathione depletion in rat hepatocytes: a mixture toxicity study with alpha, beta-unsaturated esters.Xenobiotica 31(5) , 295-307, (2001)
1. Glutathione (GSH) depletion is often reported as an early cytotoxic effect, caused by many reactive organic chemicals. In the present study, GSH depletion in primary rat hepatocytes was used as an ...
Subchronic dermal toxicity study of allyl methacrylate in rabbits.Drug Chem. Toxicol. 5(2) , 165-82, (1982)
A 28-day subchronic dermal toxicity of allyl methacrylate (AMA) was conducted in New Zealand white rabbits. Groups of six male and six female rabbits were treated with the test material at dose levels...