Methylpropenal

Names

[ CAS No. ]:
78-85-3

[ Name ]:
Methylpropenal

[Synonym ]:
α-Methylacrolein
Metharolein
2-methyl propenal
2-methylprop-2-enal
METHACROLEIN
Methylacrolein
Methacraldehyde
Methakrylaldehyd
2-Methyl-propenal
Methacrylaldehyde
2-Methylacrolein
EINECS 201-150-1
2-Propenal, 2-methyl-
2-methyl-2-propenal
2-Methylacrylaldehyde
2-methyl-acrolei
Isobutenal
MFCD00006974
2-MethylPropenal

Chemical & Physical Properties

[ Density]:
0.8±0.1 g/cm3

[ Boiling Point ]:
68.0±0.0 °C at 760 mmHg

[ Melting Point ]:
-81 °C

[ Molecular Formula ]:
C₄H₆O

[ Molecular Weight ]:
70.090

[ Flash Point ]:
-15.0±0.0 °C

[ Exact Mass ]:
70.041862

[ PSA ]:
17.07000

[ LogP ]:
0.54

[ Vapour density ]:
2.4 (vs air)

[ Vapour Pressure ]:
142.3±0.1 mmHg at 25°C

[ Index of Refraction ]:
1.385

[ Stability ]:
Stable. Incompatible with strong bases, strong oxidising agents, strong reducing agents. Light and air-sensitive. Hazardous polymerisation may occur.

[ Water Solubility ]:
6 g/100 mL (20 ºC)

MSDS

Click to get detail MSDS

Toxicological Information

CHEMICAL IDENTIFICATION

RTECS NUMBER :: OZ2625000

CHEMICAL NAME :: Methacrylaldehyde

CAS REGISTRY NUMBER :: 78-85-3

BEILSTEIN REFERENCE NO. :: 1209258

LAST UPDATED :: 199701

DATA ITEMS CITED :: 8

MOLECULAR FORMULA :: C4-H6-O

MOLECULAR WEIGHT :: 70.10

WISWESSER LINE NOTATION :: VHY1&U1

HEALTH HAZARD DATA

ACUTE TOXICITY DATA

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: Standard Draize test

ROUTE OF EXPOSURE :: Administration into the eye

SPECIES OBSERVED :: Rodent - rabbit

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Oral

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 140 mg/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LCLo - Lowest published lethal concentration

ROUTE OF EXPOSURE :: Inhalation

SPECIES OBSERVED :: Rodent - rat

DOSE/DURATION :: 125 ppm/4H

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

TYPE OF TEST :: LD50 - Lethal dose, 50 percent kill

ROUTE OF EXPOSURE :: Administration onto the skin

SPECIES OBSERVED :: Rodent - rabbit

DOSE/DURATION :: 430 uL/kg

TOXIC EFFECTS :: Details of toxic effects not reported other than lethal dose value

MUTATION DATA

TYPE OF TEST :: Mutation in microorganisms

TEST SYSTEM :: Bacteria - Salmonella typhimurium

DOSE/DURATION :: 500 umol/L

REFERENCE :: MUREAV Mutation Research. (Elsevier Science Pub. B.V., POB 211, 1000 AE Amsterdam, Netherlands) V.1- 1964- Volume(issue)/page/year: 93,305,1982

Safety Information

[ Symbol ]:

GHS02, GHS05, GHS06

[ Signal Word ]:
Danger

[ Hazard Statements ]:
H225-H301 + H311-H314

[ Precautionary Statements ]:
P210-P280-P301 + P310-P305 + P351 + P338-P310

[ Personal Protective Equipment ]:
Faceshields;full-face respirator (US);Gloves;Goggles;multi-purpose combination respirator cartridge (US);type ABEK (EN14387) respirator filter

[ Hazard Codes ]:
F:Flammable;T:Toxic;

[ Risk Phrases ]:
R11;R24/25;R26;R34

[ Safety Phrases ]:
S16-S26-S36/37/39-S45-S28A

[ RIDADR ]:
UN 2396 3/PG 2

[ WGK Germany ]:
3

[ RTECS ]:
OZ2625000

[ Packaging Group ]:
II

[ Hazard Class ]:
3

Synthetic Route

Click to get detail synthetic route

Precursor & DownStream

Precursor

DownStream

Articles

Formation of dimethylketene and methacrolein by reaction of the CH radical with acetone.

Phys. Chem. Chem. Phys. 15(11) , 4049-58, (2013)

The reaction of the methylidyne radical (CH) with acetone ((CH(3))(2)C[double bond, length as m-dash]O) is studied at room temperature and at a pressure of 4 Torr (533.3 Pa) using a multiplexed photoi...

Mechanism of the hydroxyl radical oxidation of methacryloyl peroxynitrate (MPAN) and its pathway toward secondary organic aerosol formation in the atmosphere.

Phys. Chem. Chem. Phys. 17 , 17914-26, (2015)

Methacryloyl peroxynitrate (MPAN), the acyl peroxynitrate of methacrolein, has been suggested to be an important secondary organic aerosol (SOA) precursor from isoprene oxidation. Yet, the mechanism b...

Analysis of volatile organic compounds liberated and metabolised by human umbilical vein endothelial cells (HUVEC) in vitro.

Cell Biochem. Biophys. 71(1) , 323-9, (2015)

Gas chromatography with mass spectrometric detection combined with head-space needle trap extraction as the pre-concentration technique was applied to identify and quantify volatile organic compounds ...