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1-(4-Thio-beta-D-ribofuranosyl)cytosine

Names

[ CAS No. ]:
93080-09-2

[ Name ]:
1-(4-Thio-beta-D-ribofuranosyl)cytosine

[Synonym ]:
4'-thio-cytidine
4-Amino-1-((2R,3R,4S,5R)-3,4-dihydroxy-5-hydroxymethyl-tetrahydro-thiophen-2-yl)-1H-pyrimidin-2-one
4'-Thio-β-D-ribofuranosylcytosin
1-(4-thio-β-D-ribofuranosyl)cytosine
1-<4-Thio-β-D-ribofuranosyl>-cytosin
4'-thiocytidine

Biological Activity

[Description]:

4′-Thiocytidine is a purine nucleoside analogue. Purine nucleoside analogs have broad antitumor activity targeting indolent lymphoid malignancies. Anticancer mechanisms in this process rely on inhibition of DNA synthesis, induction of apoptosis, etc[1].

[Related Catalog]:

Signaling Pathways >> Cell Cycle/DNA Damage >> Nucleoside Antimetabolite/Analog
Research Areas >> Others

[References]

[1]. Robak T, Robak P. Purine nucleoside analogs in the treatment of rarer chronic lymphoid leukemias. Curr Pharm Des. 2012;18(23):3373-88.  

Chemical & Physical Properties

[ Molecular Formula ]:
C9H13N3O4S

[ Molecular Weight ]:
259.28

[ Exact Mass ]:
259.06300

[ PSA ]:
146.90000

Related Compounds